55538-69-7

Basic information

• Product Name: 1,2-dichloro-4-phenoxy-benzene
• Synonyms: 1,2-dichloro-4-phenoxy-benzene;3,4-Dichlorophenylphenyl ether
• CAS NO: 55538-69-7
• Molecular Formula: C₁₂H₈Cl₂O
• Molecular Weight: 239.1
• Mol File: 55538-69-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 316°C at 760 mmHg
• Flash Point: 111.3°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 0.00078mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 1,2-dichloro-4-phenoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dichloro-4-phenoxy-benzene(55538-69-7)
• EPA Substance Registry System: 1,2-dichloro-4-phenoxy-benzene(55538-69-7)

Safety Data

• Hazardous Substances Data: 55538-69-7(Hazardous Substances Data)

Usage

Physical state

Colorless solid

Solubility

Soluble in organic solvents, insoluble in water

Uses

Intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds

Environmental impact

Toxic to aquatic life, may cause long-term adverse effects in the aquatic environment

Health hazards

Risk to human health through inhalation, ingestion, or skin contact

Precautions

Appropriate safety measures should be taken when handling this chemical

InChI:InChI=1/C12H8Cl2O/c13-11-7-6-10(8-12(11)14)15-9-4-2-1-3-5-9/h1-8H

Upstream product

• 56-23-5 tetrachloromethane 
• 101-84-8 diphenylether 
• 7782-50-5 chlorine 
• 7005-72-3 4-chlorodiphenyl ether 
• 64-19-7 acetic acid 
• 95-77-2 3,4-dichlorophenol 
• 98-80-6 phenylboronic acid 
• 10265-98-2 (4-chloro-3-nitro-phenyl)-phenyl ether 
• 100-67-4 potassium phenolate 
• 120-82-1 1,2,4-Trichlorobenzene 
• 108-86-1 bromobenzene 
• 39975-26-3 sodium 3,4-dichlorophenoxide 
• 74865-98-8 2-chloro-5-phenoxyaniline 
• 60854-00-4 2-nitro-4-phenoxyphenylamine 

Downstream Products

• 63646-51-5 3,4,4'-Trichlorobiphenyl ether 
• 854259-28-2 (4-bromo-phenyl)-(3,4-dichloro-phenyl)-ether 
• 1440061-26-6 C₁₆H₁₂Cl₂O₄ 
• 1440062-63-4 C₁₄H₁₃Cl₂NO₂ 
• 1440063-35-3 C₂₁H₁₅Cl₂F₂NO₃ 
• 1440059-78-8 C₂₁H₁₄Cl₃F₂NO₂ 
• 1440060-58-1 C₂₁H₁₃Cl₂F₂NO₂ 
• 1440061-96-0 C₁₆H₁₃Cl₂NO₄ 
• 88107-19-1 ethyl 2-acetylthio-3-<4-(3,4-dichlorophenoxy)benzoyl>propionate 
• 88107-18-0 ethyl 3-<4-(3,4-dichlorophenoxy)benzoyl>acrylate 
• 94402-57-0 4-(3,4-dichlorophenoxy)phenacyl chloride 
• 88112-95-2 3-<4-(3,4-dichlorophenoxy)benzoyl>acrylic acid 
• 83537-34-2 ethyl trans-3-<4-(3,4-dichlorophenoxy)benzoyl>glycidate 

Relevant articles and documents

Copper-mediated synthesis of mono- and dichlorinated diaryl ethers

An efficient synthesis of polychlorinated diphenyl ethers (PCDEs) using the Cu(OAc)2-catalyzed Chan-Lam coupling reaction is described. A library of all possible mono- and dichlorinated diphenyl ether congeners was prepared and characterized using MS, 1H, and 13C NMR spectroscopy, and Kovats retention indices. Our approach, using the optimized reaction conditions (i.e., reaction temperature, oxidizing atmosphere and base), significantly improves and simplifies the process compared to previously reported syntheses.

Studies on hypolipidemic agents. I. 3-benzoylglycidic acid derivatives

-