556113-62-3 Usage
Description
(2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid is a complex organic compound that belongs to the class of piperazine derivatives. It features a molecular structure that includes a piperazine ring, a chloro-substituted thiophenyl group, a methoxyphenyl group, and an acetic acid moiety. (2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid is known for its pharmacological properties, particularly its potential as a central nervous system stimulant and therapeutic agent for various medical conditions.
Uses
Used in Pharmaceutical Industry:
(2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid is used as a potential therapeutic agent for various medical conditions due to its pharmacological properties as a piperazine derivative. Its specific applications in medicine would require further research and testing to determine its efficacy and safety.
Used in Research and Development:
(2R)-4-[5-Chloro-2-[(4-methoxyphenyl)thio]phenyl]-2-methyl-1-piperazineacetic acid serves as a valuable compound for research and development in the field of medicinal chemistry. Its unique structure and potential pharmacological effects make it an interesting candidate for exploring new drug development opportunities and understanding the mechanisms of action for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 556113-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,6,1,1 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 556113-62:
(8*5)+(7*5)+(6*6)+(5*1)+(4*1)+(3*3)+(2*6)+(1*2)=143
143 % 10 = 3
So 556113-62-3 is a valid CAS Registry Number.
556113-62-3Relevant articles and documents
The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors
Smith, Garrick,Ruhland, Thomas,Mikkelsen, Gitte,Andersen, Kim,Christoffersen, Claus Tornby,Alifrangis, Lene Hjorth,Mork, Arne,Wren, Stephen P.,Harris, Neil,Wyman, Barry M.,Brandt, Guillaume
, p. 4027 - 4030 (2007/10/03)
Elevation of glycine levels and activation of the NMDA receptor by inhibition of the glycine transporter 1 (GlyT-1) is a potential strategy for the treatment of schizophrenia. A novel series of GlyT-1 inhibitors have been identified containing the 2-arylsulfanyl-phenylpiperazine motif. The most prominent member of this series, (R)-4-[5-chloro-2-(4-methoxy-phenylsulfanyl)- phenyl]-2-methyl-piperazin-1-yl-acetic acid (31) is a potent glycine transporter-1 inhibitor (IC50=150nM), which elevated glycine levels in rat ventral hippocampus as measured by microdialysis in vivo at doses of 1.2-4.6mg/kg s.c.
