55623-34-2

Basic information

• Product Name: methyl (9beta)-12-oxoabieta-7,13-dien-18-oate
• CAS NO: 55623-34-2
• Molecular Formula: C₂₁H₃₀O₃
• Molecular Weight: 330.4611
• Mol File: 55623-34-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 445.6°C at 760 mmHg
• Flash Point: 192.7°C
• Density: 1.07g/cm³
• Vapor Pressure: 3.9E-08mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: methyl (9beta)-12-oxoabieta-7,13-dien-18-oate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (9beta)-12-oxoabieta-7,13-dien-18-oate(55623-34-2)
• EPA Substance Registry System: methyl (9beta)-12-oxoabieta-7,13-dien-18-oate(55623-34-2)

Safety Data

• Hazardous Substances Data: 55623-34-2(Hazardous Substances Data)

Upstream product

• 3484-53-5 <1R-(1α,4aβ,4bα,6α,10aα)>-1,2,3,4,4a,4b,5,6,10,10a-Decahydro-6-hydroxy-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrencarbonsaeure-methylester 
• 108-24-7 acetic anhydride 
• 67-68-5 dimethyl sulfoxide 
• 5309-31-9 methyl 8,12α-epidioxy-13-abietan-18-oate 
• 514-10-3 (?)-abietic acid 
• 127-25-3 abietic acid methyl ester 
• 3484-53-5 (1R,4aR,6S)-6-Hydroxy-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydro-phenanthrene-1-carboxylic acid methyl ester 
• 3787-85-7 methyl 8α-hydroxy-12-oxo-13-abietan-18-oate 
• 82652-60-6 methyl 13α,14α-dihydroxyabiet-7-en-19-oate 
• 928819-28-7 C₂₃H₃₆O₅ 
• 928819-29-8 methyl 12α-chloroabietate 

Downstream Products

• 13742-23-9 (1R,4aS,10aR)-6-Hydroxy-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid methyl ester 
• 22595-48-8 18-Hydroxyferruginol 
• 13742-23-9 (1R,4aS)-6-Hydroxy-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid methyl ester 
• 30906-06-0 Methyl-12-acetoxydehydroabietat 

Relevant articles and documents

Synthesis of 4- epi-Parviflorons A, C, and E: Structure-Activity Relationship Study of Antiproliferative Abietane Derivatives

The first syntheses of 4-epi-parviflorons A, C, and E (4-epi-1-3) were achieved in 12-13 steps from commercially available (-)-abietic acid (5). All synthesized compounds, including intermediates and derivatives, were evaluated for antiproliferative activity against five human tumor cell lines. A structure-activity relationship study revealed no significant difference between Pf E and 4-epi-Pf E, the importance of two oxygen functional groups at C-11 and C-12 for antiproliferative activity, as well as a combination of carbomethoxy at C-4 and a benzoyl ester with electron-drawing group at C-12 or hydroxymethyl at C-4 and an appropriate oxidation state of ring-B/C for triple-negative breast cancer cell selectivity.

ENDOPEROXIDE DITERPENOIDS AND OTHER CONSTITUENTS FROM ABIES MAROCANA

From the acid fraction of the hexane extract of the needles of Abies marocana three endperoxide diterpenoids, methyl 12α-hydroxyabietate and a triterpenoid, in addition to other resin acids have been isolated.