55689-52-6

Basic information

• Product Name: (±)-4-(1-hydroxypropan-2-yl)phenol
• Synonyms: (±)-4-(1-hydroxypropan-2-yl)phenol
• CAS NO: 55689-52-6
• Molecular Weight: 152.193
• Mol File: 55689-52-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (±)-4-(1-hydroxypropan-2-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-4-(1-hydroxypropan-2-yl)phenol(55689-52-6)
• EPA Substance Registry System: (±)-4-(1-hydroxypropan-2-yl)phenol(55689-52-6)

Safety Data

• Hazardous Substances Data: 55689-52-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 938-96-5 2-(4-Hydroxy-phenyl)-propionic acid 

Downstream Products

• 99-93-4 4-Hydroxyacetophenone 

Relevant articles and documents

Stereoselective Oxidative Bioconjugation of Amino Acids and Oligopeptides to Aldehydes

The first stereoselective, near-equimolar, and metal-free oxidative bioconjugation of amino acids and oligopeptides to aldehydes is presented. Based on a newly developed organocatalytic oxidative concept, the C-terminal and side-chain carboxylic acid functionalities of amino acids and oligopeptides are shown to couple in a stereoselective manner to α-branched aldehydes catalyzed by a chiral primary amine and a quinone as oxidizing agent. The oxidative coupling generally proceeds in high yield. For aspartic acid, selective coupling of the side-chain, or the C-terminal carboxylic acid, is demonstrated depending on the protection strategy. The stereoselective, oxidative bioconjugation concept is extended to a series of oligopeptides where coupling to carboxylic acid functionalities is presented. Bioorthogonal linker molecules for further functionalization are obtained by merging the oxidative coupling strategy with the click concept. It is demonstrated that the configuration of the new stereocenter is determined exclusively by the organocatalyst.