557780-43-5

Basic information

• Product Name: 4-methoxy-N-morpholinobenzenesulfonamide
• Synonyms: 4-methoxy-N-morpholinobenzenesulfonamide
• CAS NO: 557780-43-5
• Molecular Weight: 272.325
• Mol File: 557780-43-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4-methoxy-N-morpholinobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-N-morpholinobenzenesulfonamide(557780-43-5)
• EPA Substance Registry System: 4-methoxy-N-morpholinobenzenesulfonamide(557780-43-5)

Safety Data

• Hazardous Substances Data: 557780-43-5(Hazardous Substances Data)

Upstream product

• 4319-49-7 1-aminomorpholine 
• 115298-63-0 phenyl(4-methoxyphenyl)iodonium triflate 
• 1330786-68-9 (3-trifluoromethylphenyl)(4-methoxyphenyl)iodonium p-toluenesulfonate 
• 50619-99-3 4,4'-dimethoxy-diphenyliodonium chloride 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 696-62-8 para-iodoanisole 
• 36301-60-7 4-aminomorpholine sulfur dioxide complex 
• 93131-74-9 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid 4-methoxyphenyl ester 
• 104-94-9 4-methoxy-aniline 
• 21130-91-6 triethoxy(4-methoxyphenyl)silane 

Downstream Products

• 14223-10-0 1-(benzylsulfonyl)-4-methoxybenzene 
• 16191-87-0 1-(vinylsulfonyl)-4-methoxybenzene 

Relevant articles and documents

Guest-controlled incommensurate modulation in a meta-rigid metal-organic framework material

Structural transitions of host systems in response to guest binding dominate many chemical processes. We report an unprecedented type of structural flexibility within a meta-rigid material, MFM-520, which exhibits a reversible periodic-to-aperiodic structural transition resulting from a drastic distortion of a [ZnO4N] node controlled by the specific host-guest interactions. The aperiodic crystal structure of MFM-520 has no three-dimensional (3D) lattice periodicity but shows translational symmetry in higher-dimensional (3 + 2)D space. We have directly visualized the aperiodic state which is induced by incommensurate modulation of the periodic framework of MFM-520·H2O upon dehydration to give MFM-520. Filling MFM-520 with CO2 and SO2 reveals that, while CO2 has a minimal structural influence, SO2 can further modulate the structure incommensurately. MFM-520 shows exceptional selectivity for SO2 under flue-gas desulfurization conditions, and the facile release of captured SO2 from MFM-520 enabled the conversion to valuable sulfonamide products. MFM-520 can thus be used as a highly efficient capture and delivery system for SO2.

Visible-Light Photoredox-Catalyzed Aminosulfonylation of Diaryliodonium Salts with Sulfur Dioxide and Hydrazines

A photoredox-catalyzed three-component synthesis of N-aminosulfonamides starting from diaryliodonium salts, hydrazines and sulfur dioxide is reported. This reaction proceeds under mild conditions at room temperature and is driven by visible light. A simple bisulfite salt can be used as a readily available and easy-to-handle sulfur dioxide source. Mechanistic studies support a catalytic photoredox pathway with the diaryliodonium salt as convenient source for aryl radicals. (Figure presented.).

A palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines

A facile route to synthesise N-aminosulfonamides through a palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines is reported. This transformation proceeds in the presence of Pd(OAc)2/XantPhos, and TBAB in 1,4-dioxane at 80°C, leading to the corresponding N-aminosulfonamides in moderate to good yields. The reaction scope has been demonstrated, and good functional tolerance is observed. A plausible mechanism is proposed through the insertion of sulfur dioxide.