55788-97-1

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 4-hydroxy-5-(phenylmethoxy)-
• Synonyms: 4-Hydroxy-5-benzyloxy-coumarin;5-benzyloxy-4-hydroxy-2H-1-benzopyran-2-one;5-Benzyloxy-4-hydroxycoumarin;5-benzyloxy-4-hydroxy-chromen-2-one
• CAS NO: 55788-97-1
• Molecular Formula: C16H12O4
• Molecular Weight: 268.26400
• Mol File: 55788-97-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 4-hydroxy-5-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 4-hydroxy-5-(phenylmethoxy)-(55788-97-1)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 4-hydroxy-5-(phenylmethoxy)-(55788-97-1)

Safety Data

• Hazardous Substances Data: 55788-97-1(Hazardous Substances Data)

Upstream product

• 4047-24-9 1-[2-(benzyloxy)-6-hydroxyphenyl]ethanone 
• 105-58-8 Diethyl carbonate 
• 699-83-2 2,6-dihydroxylacetophenone 
• 100-44-7 benzyl chloride 

Downstream Products

• 79326-08-2 5-Benzyloxy-6-methoxycoumarin 
• 79326-06-0 5-Benzyloxy-6-hydroxycoumarin 
• 79326-07-1 5-(benzyloxy)-2H-chromen-2-one 
• 79326-04-8 5-Hydroxy-6-methoxycoumarin 
• 714961-24-7 5-benzyloxy-4-chloro-2H-1-benzopyran-2-one 
• 79326-09-3 5-Benzyloxy-4-tosyloxycoumarin 

Relevant articles and documents

Synthesis and in vitro inhibitory activity on human platelet aggregation of novel properly substituted 4-(1-piperazinyl)coumarins

Pursuing our chemical and biological studies in this field, we described the multistep preparation of the new 5-, 6-, or 7-alkoxy and 7-alkoxy-8-methyl substituted 4-(1-piperazinyl)coumarins 5d-v, as well as the in vitro evaluation of their inhibitory activity on human platelet aggregation induced in platelet-rich plasma by ADP, collagen or the Ca2+ ionophore A23187. Compounds 5h-j,p,r-u showed notably high activity towards all the platelet aggregation inducers used, and the most active one, 8-methyl-4-(1-piperazinyl)- 7-(3-pyridylmethoxy)coumarin (5t), proved to be a potent in vitro antiplatelet agent.