5579-92-0 Usage
Description
Iopydol is a synthetic, water-soluble, iodinated contrast agent used in medical imaging procedures. It is designed to enhance the visibility of internal body structures during X-ray imaging by increasing the absorption of X-rays in the areas where it is applied. Iopydol is known for its low osmolarity, which helps reduce the risk of side effects and makes it suitable for various diagnostic applications.
Uses
Used in Medical Imaging:
Iopydol is used as an X-ray contrast reagent for improving the visualization of vascular structures, organs, and tissues during radiographic examinations. Its application in medical imaging includes:
1. Angiography: Iopydol is used as a contrast agent for visualizing blood vessels, helping in the diagnosis of vascular diseases, aneurysms, and other related conditions.
2. Urography: It is utilized in urography to examine the urinary system, including the kidneys, ureters, and bladder, aiding in the detection of abnormalities, blockages, or infections.
3. Arteriography: Iopydol is used in arteriography to study the arteries and diagnose conditions like arterial occlusions, aneurysms, or vascular malformations.
4. Myelography: This contrast agent is employed in myelography to examine the spinal cord and surrounding structures, assisting in the identification of spinal cord injuries, tumors, or other issues.
Used in Diagnostic Aids:
Iopydol serves as a diagnostic aid in the following applications:
1. Radiopaque Medium: It is used as a radiopaque medium to enhance the visibility of specific body structures during X-ray imaging, allowing for more accurate diagnoses.
2. Bronchography: Iopolydol is utilized in bronchography, a procedure that involves X-ray imaging of the bronchial tree, to diagnose and assess conditions like tumors, inflammation, or other abnormalities in the bronchi.
Originator
Hytrast Vial,Guerbet
Manufacturing Process
50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly
mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the
obtained dark solution was strong alkalized with sodium hydroxide. The
solvent was removed to dryness and sodium salt diiod-4-pyridone wasobtained. It was dissolved in water, filtered and equivalent quantity of glacial
acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a
powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by
heating on a water bath and added to a 15 g of monochlorohydrine added.
The mixture was heated on water bath before a dense pasty mass obtained. It
was filtered off and treated with 1 N NaOH. The obtained 1-(2,3-
dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted
hydrochloric acid. MP: 161°C.
Therapeutic Function
Diagnostic aid
Check Digit Verification of cas no
The CAS Registry Mumber 5579-92-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,7 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5579-92:
(6*5)+(5*5)+(4*7)+(3*9)+(2*9)+(1*2)=130
130 % 10 = 0
So 5579-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9I2NO3/c9-6-2-11(1-5(13)4-12)3-7(10)8(6)14/h2-3,5,12-13H,1,4H2