55814-36-3

Basic information

• Product Name: N-(4-methoxyphenyl)-2-methylbenzamide
• Synonyms: N-(4-methoxyphenyl)-2-methylbenzamide
• CAS NO: 55814-36-3
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.29
• Mol File: 55814-36-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-methoxyphenyl)-2-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-2-methylbenzamide(55814-36-3)
• EPA Substance Registry System: N-(4-methoxyphenyl)-2-methylbenzamide(55814-36-3)

Safety Data

• Hazardous Substances Data: 55814-36-3(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 933-88-0 ortho-toluoyl chloride 
• 7055-03-0 2-methyl-N-phenylbenzamide 
• 100-17-4 para-methoxynitrobenzene 
• 344874-66-4 (9H-carbazol-9-yl)(o-tolyl)methanone 
• 15813-38-4 phenyl 2-methylbenzoate 
• 623-12-1 4-chloromethoxybenzene 
• 527-85-5 o-Methylbenzamid 
• 64-17-5 ethanol 
• 87-24-1 ethyl 2-methylbenzoate 
• 156-43-4 4-Ethoxyaniline 
• 76570-32-6 N-(p-methoxyphenyl)-o-toluimidoyl chloride 
• 76570-46-2 1--4,6-diphenyl-2-pyridone 

Downstream Products

• 4778-82-9 2,3-dihydro-2-(4-methoxyphenyl)-1H-isoindol-1-one 
• 1620885-47-3 2-[1-(3,4-difluorobenzyl)-4-hydroxypiperidin-4-ylmethyl]-N-(4-methoxyphenyl)benzamide 
• 1620885-16-6 1’-(3,4-difluorobenzyl)-2-(4-methoxyphenyl)-2,4-dihydro-1H-spiro[isoquinoline-3,4’-piperidin]-1-one 
• 76570-38-2 4,6-diphenyl-5--2-pyridone 
• 76570-46-2 1--4,6-diphenyl-2-pyridone 
• 76570-32-6 N-(p-methoxyphenyl)-o-toluimidoyl chloride 

Relevant articles and documents

Nickel/Briphos-Catalyzed Direct Transamidation of Unactivated Secondary Amides Using Trimethylsilyl Chloride

Direct transamidation of secondary amides was developed via nickel catalysis. In the presence of trimethylsilyl chloride and manganese, Ni(diglyme)Cl2 with a Briphos ligand efficiently promoted the transamidation of N-aryl benzamide derivatives with primary amines to afford the corresponding secondary amides in moderate to good yields. Primary amines bearing electron-donating groups gave higher yields of the transamidation products.

Rapidly Activating Pd-Precatalyst for Suzuki-Miyaura and Buchwald-Hartwig Couplings of Aryl Esters

Esters are valuable electrophiles for cross-coupling due to their ubiquity and ease of synthesis. However, harsh conditions are traditionally required for the effective cross-coupling of ester substrates. Utilizing a recently discovered precatalyst, Pd-catalyzed Suzuki-Miyaura and Buchwald-Hartwig reactions involving cleavage of the C(acyl)-O bond of aryl esters that proceed under mild conditions are reported. The Pd(II) precatalyst is highly active because it is reduced to the Pd(0) active species more rapidly than previous precatalysts.

Copper-Catalyzed sp3 C-H Aminative Cyclization of 2-Alkyl-N-arylbenzamides: An Approach for the Synthesis of N-Aryl-isoindolinones

The synthesis of isoindolinones via copper-catalyzed sp3 C-H functionalization of 2-alkyl-N-substituted benzamides is described. This process does not require the preparation of halogenated substitutes, expensive transition metals, or toxic Sn or CO gas. This method provides an efficient approach to generate various functionalized isoindolinones.