55832-01-4Relevant articles and documents
In Vitro and in Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas
Bowler, Matthew M.,Feher, Victoria A.,Gold, Ben S.,Goullieux, Laurent,Lagiakos, H. Rachel,Li, Kelin,Ling, Yan,Moraca, Francesca,Mosior, John,Nathan, Carl F.,Ottavi, Samantha,Perkowski, Andrew J.,Ramesh, Remya,Roberts, Julia,Roubert, Christine,Sacchettini, James C.,Scarry, Sarah M.,Singh, Amrita,Tracy, William,Vendome, Jeremie,Zhang, David,Aubé, Jeffrey,Bacqué, Eric
supporting information, (2022/01/31)
A newly validated target for tuberculosis treatment is phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. The structure-activity relat
Amidinourea derivative veterinary compositions for suppression of parasitemia
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, (2008/06/13)
Therapeutic compositions containing an amidinourea are used in the treatment of animals infested with blood residing parasites, particularly parasitic protozoal infestations of the blood and blood-forming organs.
Amidinoureas
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, (2008/06/13)
This invention describes novel chemical compounds which are 1-amidino-3-phenylureas. The method of preparing these compounds and their pharmaceutical uses is also disclosed.