55854-45-0

Basic information

• Product Name: 5-METHYL-2-THIOPHENESULFONYL CHLORIDE
• Synonyms: CHEMBRDG-BB 4004665;5-METHYL-2-THIOPHENESULFONYL CHLORIDE;5-METHYL-THIOPHENE-2-SULFONYL CHLORIDE;OTAVA-BB BB7020430868;5-Methylthiophene-2-sulphonyl chloride;5-Methylthiophene-2-sulphonyl chloride 97%;2-thiophenesulfonyl chloride, 5-methyl-;5-methylthiophene-2-sulfonyl chloride(SALTDATA: FREE)
• CAS NO: 55854-45-0
• Molecular Formula: C₅H₅ClO₂S₂
• Molecular Weight: 196.68
• Product Categories: Thiophens
• Mol File: 55854-45-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 110 °C
• Flash Point: >110°(230°F)
• Appearance: /
• Density: 1.432
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: n20/D1.569
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 5-METHYL-2-THIOPHENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-2-THIOPHENESULFONYL CHLORIDE(55854-45-0)
• EPA Substance Registry System: 5-METHYL-2-THIOPHENESULFONYL CHLORIDE(55854-45-0)

Safety Data

• Hazard Codes: C,Xi,Xn
• Statements: 34-22
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8 / PGIII
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 55854-45-0(Hazardous Substances Data)

Usage

General Description

5-Methyl-2-thiophenesulfonyl chloride is a chemical compound that is commonly used in pharmaceutical and agrochemical applications. It is a derivative of thiophene, which is a heterocyclic aromatic compound. 5-METHYL-2-THIOPHENESULFONYL CHLORIDE is typically used as a reagent in the synthesis of various pharmaceuticals and agrochemicals. Additionally, it is also used as an intermediate in the production of dyes and other organic compounds. The sulfonyl chloride functional group in this compound makes it a useful reagent in organic synthesis, particularly in the formation of sulfonamides and other related compounds. However, it is important to handle this compound with caution due to its potential reactivity and corrosive nature.

InChI:InChI=1/C5H5ClO2S2/c1-4-2-3-5(9-4)10(6,7)8/h2-3H,1H3

Upstream product

• 554-14-3 2-Methylthiophene 

Downstream Products

• 5324-78-7 5-benzenesulfonyl-thiophene-2-carboxylic acid 
• 1240518-00-6 N-[1-{[3-Fluoro-4-(methyloxy)phenyl]methyl}-4-(methyloxy)-1H-indazol-3-yl]-5-methyl-2-thiophenesulfonamide 
• 1240517-46-7 4-[(4-(Methyloxy)-3-{[(5-methyl-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]benzamide 
• 1138036-44-8 2-(2,3-difluorophenyl)-1-[(5-methylthiophen-2-yl)sulfonyl]-1H-imidazole-4-carbaldehyde 
• 1138036-34-6 2-(2-fluorophenyl)-1-[(5-methylthiophen-2-yl)sulfonyl]-1H-imidazole-4-carbaldehyde 
• 5324-81-2 phenyl 5-methyl-2-thienyl sulfone 
• 53595-69-0 5-methyl-2-thiophenesulfonamide 

Relevant articles and documents

NITRIC OXIDE-RELEASING PRODRUG MOLECULE

Provided are a type of compounds that can be used for treating cardiovascular diseases and compositions containing the compounds. The compounds and the compositions can improve lipid metabolism disorders by increasing high-density lipoprotein cholesterol in blood; in addition, the compounds and the compositions can also release nitric oxide, and reduce the onset risk of cardiovascular diseases by means of relaxing blood vessels, lowering blood pressure, inhibiting platelet adhesion and aggregation and maintaining vascular tension, and thus play an important role in preventing and treating the occurrence and development of cardiovascular diseases.

CARBACEPHEM BETA-LACTAM ANTIBIOTICS

Carbacephem β-lactam antibiotics having chemical structures (I) and (II) are disclosed: including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, R1, R2 and R6 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.

NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE AT1 AND ETA RECEPTORS

The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.