55854-99-4

Basic information

• Product Name: 1-methyl-3-phenethyl-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 1-methyl-3-phenethyl-2,3-dihydroquinazolin-4(1H)-one
• CAS NO: 55854-99-4
• Molecular Weight: 266.343
• Mol File: 55854-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-phenethyl-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-phenethyl-2,3-dihydroquinazolin-4(1H)-one(55854-99-4)
• EPA Substance Registry System: 1-methyl-3-phenethyl-2,3-dihydroquinazolin-4(1H)-one(55854-99-4)

Safety Data

• Hazardous Substances Data: 55854-99-4(Hazardous Substances Data)

Upstream product

• 19050-62-5 N-(2-phenylethyl)-2-aminobenzamide 
• 64-04-0 phenethylamine 
• 118-48-9 isatoic anhydride 
• 19050-63-6 2-(methylamino)-N-phenethylbenzamide 

Relevant articles and documents

Electrochemical utilization of methanol and methanol-d4 as a C1 source to access (deuterated) 2,3-dihydroquinazolin-4(1H)-one

Herein, an electrocatalytic protocol for the synthesis of 2,3-dihydroquinazolin-4(1H)-one has been disclosed. Methanol is activated and utilized as the C1 source to cyclize with 2-aminobenzamides. This cyclization reaction proceeds conveniently (room temperature and air atmosphere) without any homogeneous metal catalysts, external oxidants, or bases. A wide variety of N,N-disubstituted 2,3-dihydroquinazolin-4(1H)-ones are obtained via this approach. Moreover, when methanol-d4 is used, a deuterated methylene motif is incorporated into the N-heterocycles, providing an efficient approach to the deuterated N-heterocycles.