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55878-45-0

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55878-45-0 Usage

General Description

2,6-Dimethoxy-4-pyrimidinecarboxylic acid methyl ester is a chemical compound with the molecular formula C9H11N3O4. It is an ester derivative of pyrimidinecarboxylic acid, with two methoxy groups attached to the 2 and 6 positions of the pyrimidine ring. This chemical is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in the development of new drugs and can also be used as a building block in organic synthesis. However, it is important to handle this compound with care, as it may present health and environmental hazards if not used properly.

Check Digit Verification of cas no

The CAS Registry Mumber 55878-45-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,8,7 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 55878-45:
(7*5)+(6*5)+(5*8)+(4*7)+(3*8)+(2*4)+(1*5)=170
170 % 10 = 0
So 55878-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O4/c1-12-6-4-5(7(11)13-2)9-8(10-6)14-3/h4H,1-3H3

55878-45-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2,6-dimethoxypyrimidine-4-carboxylate

1.2 Other means of identification

Product number -
Other names 4-Pyrimidinecarboxylic acid,2,6-dimethoxy-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55878-45-0 SDS

55878-45-0Relevant articles and documents

Aminopyrimidine Kinase Inhibitors

-

Page/Page column 80, (2011/07/06)

Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK

Total synthesis of (±)-cylindrospermopsin

Xie, Chaoyu,Runnegar, Maria T. C.,Snider, Barry B.

, p. 5017 - 5024 (2007/10/03)

The first total synthesis of the novel hepatotoxin (±)- cylindrospermopson (1) has been accomplished in 20 steps from 4-methoxy-3- methylpyridine (12) in 3.5% overall yield. The substituted piperidine A ring 19 was generated stereospecifically by a four-step sequence using the addition of trimethylsilylethynylmagnesium bromide to 12 to give 16 and stereospecific addition of vinylcuprate to 16 to form 17. The reaction of diamine 26 with cyanogen bromide produced the cyclic guanidine C ring of 27. The key step in the synthesis was bromination of ketone 31, followed by hydrogenation to liberate the free guanidine, which underwent an intramolecular S(N)2 reaction to form the tetrahydropyrimidine ring B of 32. Further hydrogenation reduced the ketone to yield 42% of 32 containing the fully functionalized tricyclic system and protected hydroxymethyluracil side chain of cylindrospermopsin. Hydrolysis of the pyrimidine in concentrated hydrochloric acid and selective monosulfation completed the synthesis of cylindrospermopsin.

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