55898-43-6

Basic information

• Product Name: DIETHYL METHYL PROPYL MALONATE
• Synonyms: DIETHYL METHYL PROPYL MALONATE;Diethyl Methylpropylpropanedioate;Diethyl 2-Methyl-2-n-propylamalonate;methylpropyl-Malonic acid. diethyl ester;2-Methyl-2-propylmalonic acid diethyl ester;Pentane-2,2-dicarboxylic acid diethyl ester;diethyl 2-methyl-2-propylpropanedioate;diethyl 2-methyl-2-propyl-propanedioate
• CAS NO: 55898-43-6
• Molecular Formula: C₁₁H₂₀O₄
• Molecular Weight: 216.27
• Product Categories: Pharmaceutical Intermediates;Miscellaneous Reagents
• Mol File: 55898-43-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 233.2°Cat760mmHg
• Flash Point: 100.3°C
• Appearance: /
• Density: 0.996g/cm³
• Vapor Pressure: 0.0565mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: DIETHYL METHYL PROPYL MALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL METHYL PROPYL MALONATE(55898-43-6)
• EPA Substance Registry System: DIETHYL METHYL PROPYL MALONATE(55898-43-6)

Safety Data

• Hazardous Substances Data: 55898-43-6(Hazardous Substances Data)

Usage

Description

DIETHYL METHYL PROPYL MALONATE, also known as Diethyl 2-Methyl-2-propylmalonate, is a colorless oil with unique chemical properties. It is a versatile reagent widely utilized in the synthesis of various compounds, particularly in the field of anaerobic alkane biodegradation.

Uses

Used in Chemical Synthesis:
DIETHYL METHYL PROPYL MALONATE is used as a reagent for the preparation of anaerobic alkane biodegradation compounds. Its chemical structure allows it to participate in various reactions, making it a valuable component in the synthesis of these environmentally friendly compounds.
Used in Environmental Applications:
DIETHYL METHYL PROPYL MALONATE is used as a key component in the development of anaerobic alkane biodegradation compounds. These compounds play a crucial role in the breakdown of alkanes in anaerobic environments, contributing to the reduction of environmental pollution and the mitigation of the impact of hydrocarbons on ecosystems.
Used in Research and Development:
DIETHYL METHYL PROPYL MALONATE is used as a research compound for exploring new chemical reactions and pathways. Its unique properties make it an interesting subject for scientists and researchers working on the development of novel chemical processes and applications.

InChI:InChI=1/C11H20O4/c1-5-8-11(4,9(12)14-6-2)10(13)15-7-3/h5-8H2,1-4H3

Upstream product

• 141-52-6 sodium ethanolate 
• 2163-48-6 diethyl propylmalonate 
• 74-88-4 methyl iodide 
• 53651-72-2 diethyl allylmethylmalonate 
• 19157-51-8 ethyl 2-ethoxycarbonyl-2-methyl-4-pentynoate 
• 106-94-5 propyl bromide 
• 609-08-5 Diethyl methylmalonate 
• 107-08-4 1-iodo-propane 
• 105-53-3 diethyl malonate 

Downstream Products

• 92155-95-8 diethyl 2-(2-methylpentyl)malonate 
• 39255-32-8 manzanate 
• 105-30-6 2-methylpentan-1-ol 
• 25346-33-2 1-bromo-2-methylpentane 
• 68734-78-1 2-Methyl-2-(phenylthio)-pentansaeureethylester 
• 78-26-2 2-methyl-2-propyl-1,3-propanediol 

Relevant articles and documents

Synthesis and mass spectra of rearrangement bio-signature metabolites of anaerobic alkane degradation via fumarate addition

Metabolite profiling in anaerobic alkane biodegradation plays an important role in revealing activation mechanisms. Apart from alkylsuccinates, which are considered to be the usual biomarkers via fumarate addition, the downstream metabolites of C-skeleton rearrangement can also be regarded as biomarkers. However, it is difficult to detect intermediate metabolites in both environmental samples and enrichment cultures, resulting in lacking direct evidence to prove the occurrence of fumarate addition pathway. In this work, a synthetic method of rearrangement metabolites was established. Four compounds, namely, propylmalonic acid, 2-(2-methylbutyl)malonic acid, 2-(2-methylpentyl)malonic acid and 2-(2-methyloctyl)malonic acid, were synthesized and determined by four derivatization approaches. Besides, their mass spectra were obtained. Four characteristic ions were observed at m/z 133 + 14n, 160 + 28n, 173 + 28n and [M - (45 + 14n)]+ (n = 0 and 2 for ethyl and n-butyl esters, respectively). For methyl esterification, mass spectral features were m/z 132, 145 and [M - 31]+, while for silylation, fragments were m/z 73, 147, 217, 248, 261 and [M - 15]+. These data provide basis on identification of potential rearrangement metabolites in anaerobic alkane biodegradation via fumarate addition.

Pd-C-induced catalytic transfer hydrogenation with triethylsilane

(Chemical Equation Presented) In situ generation of molecular hydrogen by addition of triethylsilane to palladium-charcoal catalyst results in rapid and efficient reduction of multiple bonds, azides, imines, and nitro groups, as well as benzyl group and allyl group deprotection under mild, neutral conditions.