55908-34-4

Basic information

• Product Name: A-METHYL-4-QUINOLINEMETHANOL
• Synonyms: 4-QUINOLINEMETHANOL, A-METHYL-;A-METHYL-4-QUINOLINEMETHANOL;4-Quinolinemethanol,α-methyl-;1-Quinolin-4-yl-ethanol
• CAS NO: 55908-34-4
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.214
• Mol File: 55908-34-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: A-METHYL-4-QUINOLINEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: A-METHYL-4-QUINOLINEMETHANOL(55908-34-4)
• EPA Substance Registry System: A-METHYL-4-QUINOLINEMETHANOL(55908-34-4)

Safety Data

• Hazardous Substances Data: 55908-34-4(Hazardous Substances Data)

Upstream product

• 4363-93-3 quinoline-4-carboxaldehyde 
• 917-64-6 methyl magnesium iodide 
• 19020-26-9 4-ethylquinoline 
• 74-88-4 methyl iodide 
• 75-16-1 methylmagnesium bromide 
• 91-22-5 quinoline 
• 64-17-5 ethanol 

Downstream Products

• 4945-29-3 4-vinylquinoline 
• 19020-26-9 4-ethylquinoline 
• 60814-30-4 4-acetylquinoline 
• 168843-97-8 4-[1-(4-Methoxy-benzyloxy)-ethyl]-quinoline 
• 161906-99-6 (R)-4-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2-trimethylsilanylethynyl-2H-quinoline-1-carboxylic acid phenyl ester 
• 161824-79-9 (1aS,2S,7bR)-7b-Acetyl-2-((Z)-6-trimethylsilanyl-hex-3-ene-1,5-diynyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester 
• 161824-78-8 (1aS,2S,7bR)-7b-Acetyl-2-ethynyl-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester 
• 169103-36-0 (1aS,2S,7bS)-2-Ethynyl-7b-((S)-1-hydroxy-ethyl)-1a,7b-dihydro-2H-1-oxa-3-aza-cyclopropa[a]naphthalene-3-carboxylic acid phenyl ester 
• 161906-98-5 4-[(S)-1-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-quinoline 
• 161824-77-7 (R)-2-Ethynyl-4-((S)-1-hydroxy-ethyl)-2H-quinoline-1-carboxylic acid phenyl ester 

Relevant articles and documents

Synthetic studies on antibiotic dynemicin A. Synthesis of cyclic enediyne model compound of dynemicin A

Dynemicin A, a potent antitumor antibiotic has novel 10-membered cyclic enediyne moiety. The bicyclo[7.3.1]-tridecadiyne system having aniline moiety of this antibiotic was designed and synthesized from lepidine in 10 steps. The synthesized compound can be cycloaromatized to Bergman product via pinacol rearrangement under acidic condition, and also exhibited DNA cleaving activity.

METHOD OF PREPARING SILYLATIVE-REDUCED N-HETEROCYCLIC COMPOUND USING ORGANOBORON CATALYST

Provided is a method of preparing a silylative-reduced N-heterocyclic compound by reducing an N-heteraromatic compound including a sp2 hybridized nitrogen atom while simultaneously introducing a silyl group into a beta-position with respect to a nitrogen atom of the N-heteroaromatic compound, using a silane compound, in the presence of an organoboron catalyst.

Palladium-catalyzed Minisci reaction with simple alcohols

A palladium-catalyzed coupling of N-heterocycles with simple alcohols was achieved. The reaction is initiated by peroxide and does not require the use of stoichiometric acid for activation of the heterocycle.