55999-90-1Relevant articles and documents
Structure-based redesign of an edema toxin inhibitor
Chen, Deliang,Ma, Lili,Kanalas, John J.,Gao, Jian,Pawlik, Jennifer,Jimenez, Maria Estrella,Walter, Mary A.,Peterson, Johnny W.,Gilbertson, Scott R.,Schein, Catherine H.
experimental part, p. 368 - 376 (2012/03/22)
Edema factor (EF) toxin of Bacillus anthracis (NIAID category A), and several other toxins from NIAID category B Biodefense target bacteria are adenylyl cyclases or adenylyl cyclase agonists that catalyze the conversion of ATP to 3′,5′-cyclic adenosine mo
SUBSTITUTED N-ARYL-9-OXO-9H-FLUORENE-1-CARBOXAMIDES AND ANALOGS AS ACTIVATOR OF CASPASES AND INDUCERS OF APOPTOSIS
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Page/Page column 34, (2010/10/20)
The present invention is directed to substituted N-aryl-9-oxo-9H-fluorene-1-carboxamides and analogs thereof, represented by the general Formula I: (I) wherein R1-R8, X and Ar are defined herein. The present invention also relates to the discovery that co
