560131-60-4

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 1-(3-carboxyphenyl)-3-(2-hydroxyethyl)-
• CAS NO: 560131-60-4
• Molecular Formula: C18H15NO5
• Molecular Weight: 325.321
• Mol File: 560131-60-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 1-(3-carboxyphenyl)-3-(2-hydroxyethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 1-(3-carboxyphenyl)-3-(2-hydroxyethyl)-(560131-60-4)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 1-(3-carboxyphenyl)-3-(2-hydroxyethyl)-(560131-60-4)

Safety Data

• Hazardous Substances Data: 560131-60-4(Hazardous Substances Data)

Upstream product

• 560131-59-1 C₂₀H₁₇NO₆ 

Downstream Products

• 560131-61-5 C₂₀H₁₉NO₅ 

Relevant articles and documents

The discovery and structure-activity relationships of indole-based inhibitors of glutamate carboxypeptidase II

A series of N-substituted 3-(2-mercaptoethyl)-1H-indole-2-carboxylic acids were synthesized as inhibitors of glutamate carboxypeptidase II (GCPII). Those containing carboxybenzyl or carboxyphenyl groups at the N-position exhibited potent inhibitory activity against GCPII. These indole-based compounds represent the first example of achiral GCPII inhibitors and demonstrate greater tolerance of the GCPII active site for ligands with significant structural difference from the endogenous substrate, N-acetyl-aspartylglutamate.