56058-19-6

Basic information

• Product Name: 2-(2-butoxyethyl)-1H-isoindole-1,3(2H)-dione
• Synonyms: 2-(2-butoxyethyl)-1H-isoindole-1,3(2H)-dione;1H-isoindole-1,3(2H)-dione, 2-(2-butoxyethyl)-
• CAS NO: 56058-19-6
• Molecular Formula: C14H17NO3
• Molecular Weight: 247.28968
• Mol File: 56058-19-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 361.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.1376 g/cm3
• PKA: -2.25±0.20(Predicted)
• CAS DataBase Reference: 2-(2-butoxyethyl)-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-butoxyethyl)-1H-isoindole-1,3(2H)-dione(56058-19-6)
• EPA Substance Registry System: 2-(2-butoxyethyl)-1H-isoindole-1,3(2H)-dione(56058-19-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 56058-19-6(Hazardous Substances Data)

Usage

Chemical class

Isoindole-1,3(2H)-dione derivatives

Molecular weight

275.34 g/mol

Physical appearance

White to off-white solid

Melting point

82-86°C

Solubility

Sparingly soluble in water

Uses

Building block in the synthesis of pharmaceuticals and agrochemicals

Unique properties

Potential applications in the development of new drugs and agricultural products due to its unique chemical structure.

Upstream product

• 524-38-9 N-hydroxyphthalimide 
• 111-34-2 -butyl vinyl ether 

Downstream Products

• 6338-52-9 2-butoxyethylamine 

Relevant articles and documents

Regioselective Radical Alkene Amination Strategies by Using Phosphite-Mediated Deoxygenation

Nitrogen-containing compounds are an essential motif in all disciplines of chemistry and the efficient synthesis of these frameworks is a highly sought-after goal. Presented here is a summary of recent efforts conducted by our group to develop radical-mediated amination strategies for the formal synthesis of primary amines from alkenes with exclusive anti-Markovnikov regioselectivity. We have found that N-hydroxyphthalimide is an effective reagent capable of supplying both the N and H atoms for alkene hydroamination in a group transfer radical addition-type mechanism. Furthermore, allyl-oxyphthalimide derivatives are similarly capable of radical group transfers and allow for the aminoallylation of an external alkene.

Mitodepressive effect of some N substituted phthalimides on Lepidium sativum L.

-