56105-99-8

Basic information

• Product Name: (4-CYANOPHENYL)METHANESULFONYL CHLORIDE
• Synonyms: (4-CYANOPHENYL)METHANESULFONYL CHLORIDE;BENZENEMETHANESULFONYL CHLORIDE, 4-CYANO;(4-Cyanophenyl)methylsulphonyl chloride, 4-[(Chlorosulphonyl)methyl]benzonitrile;4-Cyanobenzylsulphonyl chloride;(4-Cyanophenyl)methanesulphonyl chloride;4-[(Chlorosulphonyl)methyl]benzonitrile, alpha-(Chlorosulphonyl)-4-cyanotoluene
• CAS NO: 56105-99-8
• Molecular Formula: C₈H₆ClNO₂S
• Molecular Weight: 215.66
• Mol File: 56105-99-8.mol
• Article Data: 14

Chemical Properties

• Melting Point: 99.5 °C
• Boiling Point: 376.225°C at 760 mmHg
• Flash Point: 181.335°C
• Appearance: /
• Density: 1.459g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Tetrahydronfuran (Very Slightly, Heated)
• Stability: Moisture Sensitive
• CAS DataBase Reference: (4-CYANOPHENYL)METHANESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CYANOPHENYL)METHANESULFONYL CHLORIDE(56105-99-8)
• EPA Substance Registry System: (4-CYANOPHENYL)METHANESULFONYL CHLORIDE(56105-99-8)

Safety Data

• Hazardous Substances Data: 56105-99-8(Hazardous Substances Data)

Usage

General Description

(4-Cyanophenyl)methanesulfonyl chloride, also known as 4-Cyanobenzenesulfonyl chloride, is a highly reactive and versatile chemical compound. It is commonly used as a reagent in organic synthesis, particularly in the preparation of sulfonamides and sulfonylureas. (4-CYANOPHENYL)METHANESULFONYL CHLORIDE is known for its ability to form stable bonds with a wide range of functional groups, making it an important building block in the production of pharmaceuticals and agrochemicals. It is also used in the synthesis of dyes, fluorescent probes, and other specialty chemicals. However, (4-Cyanophenyl)methanesulfonyl chloride is a hazardous substance and must be handled with caution, as it can cause irritation to the skin, eyes, and respiratory system upon contact.

InChI:InChI=1/C8H6ClNO2S/c9-13(11,12)6-8-3-1-7(5-10)2-4-8/h1-4H,6H2

Upstream product

• 17356-08-0 thiourea 
• 874-86-2 4-cyanobenzyl chloride 
• 56105-98-7 sodium (4-cyanophenyl)methanesulfonate 
• 17201-43-3 4-cyanobenzyl bromide 
• 7757-83-7 sodium sulfite 

Downstream Products

• 1417156-42-3 1-(4-cyanophenyl)-3-(4-methoxyphenyl)-2-thia-3-azabicyclo[3.1.0]hexane 2,2-dioxide 
• 1417156-28-5 N-allyl-1-(4-cyanophenyl)-N-(4-methoxyphenyl)methanesulfonamide 
• 1039967-79-7 1-(4-cyanophenyl)-N-(4-methoxyphenyl)methanesulfonamide 
• 191868-25-4 (R)-N₅-[Amino(nitroimino)methyl]-N₂-(diphenylacetyl)-N-[[4-(methylaminosulphonylmethyl)phenyl]methyl]-ornithinamide 
• 191868-24-3 4-(Methylaminosulphonylmethyl)benzenemethanamine 

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Clean and economic synthesis of alkanesulfonyl chlorides from S-alkyl isothiourea salts via bleach oxidative chlorosulfonation

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