5613-27-4

Basic information

• Product Name: 5-Bromo-2,3-dimethylbenzoic acid
• Synonyms: 5-Bromo-2,3-dimethylbenzoic acid
• CAS NO: 5613-27-4
• Molecular Weight: 229.073
• EINECS: -0
• Mol File: 5613-27-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-Bromo-2,3-dimethylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2,3-dimethylbenzoic acid(5613-27-4)
• EPA Substance Registry System: 5-Bromo-2,3-dimethylbenzoic acid(5613-27-4)

Safety Data

• Hazardous Substances Data: 5613-27-4(Hazardous Substances Data)

Upstream product

• 603-79-2 2,3-dimethylbenzoic acid 

Downstream Products

• 1229245-31-1 5-bromo-N-cyclopropyl-2,3-dimethylbenzamide 
• 5613-28-5 methyl 5-bromo-2,3-dimethylbenzoate 
• 1229245-29-7 N-cyclopropyl-5-(3-methoxypropyl)-2,3-dimethylbenzamide 
• 1229245-30-0 N-cyclopropyl-5-[(1E)-3-methoxy-1-propen-1-yl]-2,3-dimethylbenzamide 
• 1194488-46-4 N-[5-(3-methoxypropyl)-2,3-dimethylbenzyl]cyclopropanamine 
• 1427406-60-7 C₂₃H₂₁F₂NO₃ 
• 1427408-42-1 isopropyl 2-[3-[(2,3-dimethyl-5-phenylphenyl)methylamino]-2,4-difluorophenoxy]acetate 
• 1427408-41-0 3-[(2,3-dimethyl-5-phenylphenyl)methylamino]-2,4-difluorophenol 
• 1427408-40-9 N-(2,6-difluoro-3-hydroxyphenyl)-2,3-dimethyl-5-phenylbenzamide 
• 1427406-59-4 C₂₄H₂₃F₂NO₃ 
• 1427408-38-5 C₂₇H₂₉F₂NO₃ 
• 1427408-37-4 4-fluoro-3-[[5-(3-fluorophenyl)-2,3-dimethylphenyl]methylamino]-2-methylphenol 
• 1427408-36-3 N-(6-fluoro-3-hydroxy-2-methylphenyl)-5-(3-fluorophenyl)-2,3-dimethylbenzamide 
• 1427406-56-1 C₂₃H₁₉F₄NO₃ 

Relevant articles and documents

BENZOPYRAZOLE COMPOUND USED AS RHO KINASE INHIBITOR

The invention relates to a benzopyrazole compound used as RHO kinase inhibitor, a pharmaceutical composition and uses thereof for preparing an RHO kinase inhibiting drug, and more specifically to said compound of formula (I-1), a pharmaceutically acceptable salt and isomer thereof.

RENIN INHIBITORS

Renin inhibitors, which are spirocyclic piperidine amides, of structural formula (I) and pharmaceutical compositions thereof useful in the treatment of cardiovascular diseases and renal insufficiency, wherein n, for each instance in which it occurs, is independently 0, 1, or 2; R1 is hydrogen, C1-6 -alkyl or C3-6 -cycloalkyl, wherein said C1-6 -alkyl or C3-6 -cycloalkyl group can be independently substituted with 1-3 halogens; A is (i) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic monocyclic ring or (ii) a five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring which is fused to another five- or six-membered saturated or unsaturated heterocyclic or carbocyclic ring, V is a bond or -(C=O)-, -CH(OH)-, -CH2- or =CH-; U is a bond or -CH2-, or for the case when V is =CH-, U is -CH=; X is =CH-, =CF-, =C(OR3)-, or -C=O-; and Y is =CH-, =CF-, =N-, or for the case when X is -C=O-, Y is -N(R3)-.

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.