56164-42-2

Basic information

• Product Name: 3-Chloro-1H-Pyrrole-2-carboxaldehyde
• Synonyms: 3-Chloro-1H-Pyrrole-2-carboxaldehyde;3-Chloro-1H-pyrrole-2-carbaldehyde
• CAS NO: 56164-42-2
• Molecular Formula: C₅H₄ClNO
• Molecular Weight: 129.54436
• Mol File: 56164-42-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 251.5±20.0 °C(Predicted)
• Appearance: /
• Density: 1.417±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 13.62±0.50(Predicted)
• CAS DataBase Reference: 3-Chloro-1H-Pyrrole-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-1H-Pyrrole-2-carboxaldehyde(56164-42-2)
• EPA Substance Registry System: 3-Chloro-1H-Pyrrole-2-carboxaldehyde(56164-42-2)

Safety Data

• Hazardous Substances Data: 56164-42-2(Hazardous Substances Data)

Usage

Description

3-Chloro-1H-Pyrrole-2-carboxaldehyde is a chemical compound that belongs to the class of pyrrole derivatives. It is a pale yellow to brownish solid, known for its mild, selective, and efficient reactions in various synthetic transformations. This makes it a valuable tool in the field of organic chemistry.
Used in Pharmaceutical Industry:
3-Chloro-1H-Pyrrole-2-carboxaldehyde is used as a building block in organic synthesis for the preparation of pharmaceuticals. Its versatile chemical properties allow for the creation of a wide range of drug candidates.
Used in Agrochemical Industry:
3-Chloro-1H-Pyrrole-2-carboxaldehyde is also used as a building block in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural chemicals.
Used in Organic Synthesis:
3-Chloro-1H-Pyrrole-2-carboxaldehyde is used as a chemical intermediate for the preparation of other fine chemicals, thanks to its reactivity and the mild conditions under which it participates in reactions.
Used in Antimicrobial and Antifungal Applications:
Due to its antimicrobial and antifungal properties, 3-Chloro-1H-Pyrrole-2-carboxaldehyde has potential applications in the development of new drugs, particularly for treating infections caused by resistant strains of bacteria and fungi.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 153633-34-2 3-chloro-1-(p-toluenesulfonyl)pyrrole 

Downstream Products

• 111455-93-7 3-chloro-N-methyl-2-formylpyrrole 
• 171626-90-7 3-chloro-2-formyl-1-(p-toluenesulfonyl)pyrrole 
• 171626-83-8 7-{5-[3-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrol-2-yl]-3-methoxy-furan-2-yl}-4,5-dihydro-indole-1-carboxylic acid tert-butyl ester 
• 171626-79-2 2-(1-{5-[3-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrol-2-yl]-3-methoxy-furan-2-yl}-vinyl)-pyrrole-1-carboxylic acid tert-butyl ester 
• 171626-75-8 1-[3-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrol-2-yl]-4-(tetrahydro-pyran-2-yloxy)-butane-1,3-dione 
• 171626-93-0 1-[3-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrol-2-yl]-3-hydroxy-4-(tetrahydro-pyran-2-yloxy)-butan-1-one 
• 188491-48-7 3-Chloro-2-(5-cyclohexylidenemethyl-4-methoxy-furan-2-yl)-pyrrole-1-carboxylic acid tert-butyl ester 
• 171626-78-1 3-Chloro-2-[5-(cyclohexyl-hydroxy-methyl)-4-methoxy-furan-2-yl]-pyrrole-1-carboxylic acid tert-butyl ester 
• 171626-76-9 3-Chloro-2-(4-methoxy-furan-2-yl)-1-(toluene-4-sulfonyl)-1H-pyrrole 
• 171626-77-0 [5-(3-Chloro-1H-pyrrol-2-yl)-3-methoxy-furan-2-yl]-cyclohexyl-methanol 
• 171626-92-9 1-[3-Chloro-1-(toluene-4-sulfonyl)-1H-pyrrol-2-yl]-ethanol 
• 171626-91-8 2-acetyl-3-chloro-1-tosylpyrrole 
• 316351-99-2 1-benzyl-3-chloro-2-[1-(2-methoxyprop-2-en-1-yl)oxyprop-2-en-1-yl]pyrrole 
• 316351-98-1 1-benzyl-3-chloro-2-(1-hydroxyprop-2-en-1-yl)pyrrole 

Relevant articles and documents

Synthesis of 3-chloro-2-formylpyrrole derivatives

Regioselective deprotonation of 3-chloro-1-tosylpyrrole is used to prepare the 2-formyl derivative. Application of this chemistry in a synthesis of the left hand pyrrolo-furan substructure of roseophilin is described.