56211-88-2

Basic information

• Product Name: n-dodecanoyl-D-phenylalanine
• Synonyms: n-dodecanoyl-D-phenylalanine
• CAS NO: 56211-88-2
• Molecular Weight: 347.498
• Mol File: 56211-88-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: n-dodecanoyl-D-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: n-dodecanoyl-D-phenylalanine(56211-88-2)
• EPA Substance Registry System: n-dodecanoyl-D-phenylalanine(56211-88-2)

Safety Data

• Hazardous Substances Data: 56211-88-2(Hazardous Substances Data)

Upstream product

• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 673-06-3 D-(R)-phenylalanine 
• 75531-11-2 N-dodecanoyl-L-phenylalanine 4-nitrophenylester 
• 75531-12-3 N-dodecanoyl-D-phenylalanine 4-nitrophenylester 
• 112-16-3 n-dodecanoyl chloride 
• 75531-07-6 p-nitrophenyl n-dodecanoyl-D(L)-phenylalaninate 
• 75531-12-3 p-nitrophenyl N-dodecanoyl-D-phenylalaninate 

Relevant articles and documents

Enantioselective hydrolysis of long chain α-amino acid esters by chiral sulfur-containing macrocyclic metallomicelles

A novel chiral lipophilic sulfur-containing macrocyclic ligand 5 with bis-pendant alcohols in the proximity of the coordination center has been synthesized. Its metal ion complexes have been investigated as catalysts for the enantioselective hydrolysis of long chain α-amino acid esters in aqueous comicellar solution with Brij35. Large rate accelerations (up to 220 times) and moderate enantioselectivities (up to 4.85 (k(S)/k(R))) employing the macrocyclic 5-Cu2+ have been observed, whereas the acyclic 3-Cu2+ exhibits less reactivity and stereoselectivity. Taking the analogous ligand 4, lacking the hydroxy groups leads to a dramatic rate decrease, and an inversion of enantioselectivity is observed. The pKa value of the hydroxyl bound to Cu2+ is determined to be pKa=7.2 under our micellar reaction conditions.

Enantioselective ester hydrolysis by an achiral catalyst co-embedded with chiral amphiphiles into a vesicle membrane

Co-embedding of an amphiphilic non-chiral hydrolysis catalyst with amphiphilic chiral additives into the membrane of a phospholipid vesicle induces different rates of ester hydrolysis for enantiomeric amino acid esters.

Steric-control for the enantioselective hydrolysis of amino acid esters in hybrid membrane systems.

The enantioselective hydrolysis of the amino acid esters, p-nitrophenyl-N-dodecanoyl-D(L)-phenylalaninates (C(12)-D(L)-Phe-PNP) catalyzed by active tripeptide, N-(benzyloxycarbonyl)-L-phenylalanyl-L-histidyl-L-leucine (Z-PheHisLeu) in the presence of coag