56221-68-2

Basic information

• Product Name: 8-demethyl-8-amino-D-riboflavin
• CAS NO: 56221-68-2
• Molecular Weight: 377.357
• Mol File: 56221-68-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 8-demethyl-8-amino-D-riboflavin(CAS DataBase Reference)
• NIST Chemistry Reference: 8-demethyl-8-amino-D-riboflavin(56221-68-2)
• EPA Substance Registry System: 8-demethyl-8-amino-D-riboflavin(56221-68-2)

Safety Data

• Hazardous Substances Data: 56221-68-2(Hazardous Substances Data)

Upstream product

• 50-69-1 D-ribose 
• 119-32-4 4-Methyl-3-nitroanilin 
• 51093-55-1 ¹⁴N₅-roseflavin 
• 87-39-8 violuric acid 

Downstream Products

• 62746-55-8 8-methylamino-8-demethyl-riboflavin 

Relevant articles and documents

Photo-degradation behaviour of roseoflavin in some aqueous solutions

An absorption and emission spectroscopic characterization of roseoflavin (8-dimethylamino-8-demethyl-riboflavin, RoF) in aqueous solutions was carried out. The studies were concentrated on roseoflavin in pH 8 phosphate buffer. Absorption cross-section spectra, fluorescence excitation spectra, fluorescence quantum distributions, fluorescence quantum yields and fluorescence lifetimes were determined. The fluorescence of RoF is quenched by photo-induced intra-molecular charge-transfer at room temperature. The photo-degradation of RoF in un-buffered water, in Tris-HCl buffer, and in phosphate buffer was studied. Phosphate buffer and to a smaller extent Tris buffer catalyse the RoF photo-degradation. Photo-excitation of the primary photoproduct, 8-methylamino-riboflavin (8-MNH-RF), enhanced the RoF degradation by triplet 8-MNH-RF - singlet RoF excitation transfer with subsequent triplet-state RoF degradation.

FLAVIN DERIVATIVES

The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.