56309-56-9

Basic information

• Product Name: 2-Isopropylphenyl isocyanate
• Synonyms: 2-ISOPROPYLPHENYL ISOCYANATE;1-Isocyanato-2-isopropyl-benzene;o-isopropylphenylisocyanate;2-Isopropylphenyl Isocyante;Benzene, 1-isocyanato-2-(1-methylethyl)- (9CI);2-ISOPROPYLPHENYL ISOCYANATE 95%;1-Isocyanato-2-propan-2-ylbenzene;Benzene, 1-isocyanato-2-(1-methylethyl)-
• CAS NO: 56309-56-9
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.2
• EINECS: 260-105-4
• Product Categories: ISOPROPYL;Isocyanates;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 56309-56-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 66-67 °C5 mm Hg(lit.)
• Flash Point: 190 °F
• Appearance: Clear colorless/Liquid
• Density: 1.019 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.128mmHg at 25°C
• Refractive Index: n20/D 1.524(lit.)
• Water Solubility: Insoluble in water.
• Sensitive: Moisture Sensitive
• BRN: 3588928
• CAS DataBase Reference: 2-Isopropylphenyl isocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Isopropylphenyl isocyanate(56309-56-9)
• EPA Substance Registry System: 2-Isopropylphenyl isocyanate(56309-56-9)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-26-36
• RIDADR: UN 2206 6.1/PG 3
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 56309-56-9(Hazardous Substances Data)

Usage

Uses

2-Isopropylphenyl isocyanate is used as intermediates.

InChI:InChI=1/C10H11NO/c1-8(2)9-5-3-4-6-10(9)11-7-12/h3-6,8H,1-2H3

Upstream product

• 124-38-9 carbon dioxide 
• 2446-83-5 di-isopropyl azodicarboxylate 
• 643-28-7 2-isopropylaniline 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 75-44-5 phosgene 
• 851199-82-1 2-isopropylphenyl trifluoromethanesulfonate 
• 917-61-3 sodium isocyanate 
• 88-69-7 2-(1-methylethyl)phenol 

Downstream Products

• 38103-25-2 1-{[(E)-4-Chloro-2-methyl-phenylimino]-methyl}-3-(2-isopropyl-phenyl)-1-methyl-urea 
• 23122-33-0 C₁₈H₂₀N₂O₄ 
• 38008-54-7 (2-Isopropyl-phenyl)-carbamic acid 3-methylsulfanylcarbonylamino-phenyl ester 
• 128255-24-3 (2-Isopropyl-phenyl)-carbamic acid 2-piperidin-1-yl-ethyl ester; hydrochloride 
• 124420-85-5 1-(2-Isopropyl-phenyl)-3-pyridin-4-yl-urea 
• 131449-95-1 (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-isopropyl-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid 
• 1098477-89-4 1-(2-hydroxy-4-nitrophenyl)-3-(2-isopropylphenyl)urea 
• 1260072-97-6 4-{([(2'-isopropylphenyl)amino]carbonyl)amino}benzenesulfonamide 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS, AND METHODS FOR SELECTIVELY INHIBITING β-GLUCURONIDASES AND ALLEVIATING SIDE EFFECTS ASSOCIATED WITH DRUG TREATMENT INDUCED DIARRHEA

The present disclosure describes compounds and compositions that inhibit β-glucuronidase activity, and methods for attenuating the side effects of one or more drugs and improving the efficacy of drugs by administration of selective β-glucuronidase inhibitors.

Palladium-catalyzed synthesis of N-aryl carbamates

An efficient synthesis of aryl carbamates was achieved by introducing alcohols into the reaction of palladium-catalyzed cross-coupling of ArX (X = Cl, OTf) with sodium cyanate. The use of aryl triflates as electrophilic components in this transformation a

A facile method for preparation of aromatic isocyanates using bis(trichloromethyl)carbonate

A facile synthesis of aromatic isocyanates using bis(trichloromethyl)carbonate (BTC) is reported with high yields of products. BTC is used to supply phosgene in situ in stoichiometric amounts.