56355-62-5

Basic information

• Product Name: METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE
• Synonyms: METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE;Ethyl 2-(2-bromo-5-methylthiazol-4-yl)acetate;Ethyl2-bromo-5-methyl-1,3-thiazole-4-carboxylate
• CAS NO: 56355-62-5
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 250.11292
• Mol File: 56355-62-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE(56355-62-5)
• EPA Substance Registry System: METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE(56355-62-5)

Safety Data

• Hazardous Substances Data: 56355-62-5(Hazardous Substances Data)

Usage

Description

METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE is a thiazole derivative with the molecular formula C7H8BrNO2S. It is a heterocyclic organic compound that features a five-membered ring composed of three carbon atoms, one nitrogen atom, and one sulfur atom. METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE is widely recognized for its role as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds, with its specific applications varying across different industries.

Uses

Used in Pharmaceutical Industry:
METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel drug molecules. Its unique structure allows it to be a building block in creating therapeutic agents that address a range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE is utilized as an intermediate in the production of agrochemicals. Its incorporation aids in the development of compounds that can enhance crop protection, productivity, and overall agricultural sustainability.
Used in Organic Synthesis:
METHYL (2-BROMO-5-METHYL-1,3-THIAZOL-4-YL)ACETATE is also employed as an intermediate in organic synthesis for creating a variety of organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of specialty chemicals used in various applications, such as dyes, fragrances, and other industrial products.

Upstream product

• 57332-84-0 3-bromo-2-oxo-butyric acid ethyl ester 
• 15933-07-0 Ethyl 2-oxobutanoate 
• 72054-60-5 2-amino-5-methylthiazole-4-carboxylic acid ethyl ester 

Downstream Products

• 1187836-86-7 (2-bromo-5-methyl-1,3-thiazol-4-yl)methanol 
• 1204747-43-2 C₂₁H₁₇N₃O₂S 

Relevant articles and documents

Design and synthesis of novel triazole derivatives containing γ-lactam as potential antifungal agents

A series of novel triazole derivatives containing γ-lactam were designed and synthesized, and their structures were confirmed by 1H NMR, 13C NMR and HRMS. The in vitro antifungal activities of the target compounds were evaluated. The results showed that all of the compounds exhibited stronger activity against the six clinically important fungi tested than fluconazole. 3D and 3E showed comparative activity against the fungi tested except for Candida glabrata and Aspergillus fumigatus as voriconazole. In addition, the docking model for 2A and CYP51 was investigated.

HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS

This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts thereof, wherein R12 is a hydroxylated alkyl group and R9 contains a heterocyclic ring. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating atherosclerosis and preventing atherosclerotic disease events.