56379-89-6 Usage
General Description
Z-PHE-OH is a chemical compound with the molecular formula C16H19NO3. It is a derivative of phenylalanine, an essential amino acid, and is commonly used in the synthesis of pharmaceuticals and as a building block in organic chemistry. Z-PHE-OH is a white crystalline solid with a melting point of 136-139°C and is slightly soluble in water but soluble in organic solvents such as ethanol and methanol. It is also known by its IUPAC name, (2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid, and is widely used in the research and development of peptide-based drugs and biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 56379-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,7 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 56379-89:
(7*5)+(6*6)+(5*3)+(4*7)+(3*9)+(2*8)+(1*9)=166
166 % 10 = 6
So 56379-89-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO4/c18-15(19)14(11-12-7-3-1-4-8-12)17-16(20)21-13-9-5-2-6-10-13/h1-10,14H,11H2,(H,17,20)(H,18,19)
56379-89-6Relevant articles and documents
Revolutionary phosgene-free synthesis of α-amino acid N-carboxyanhydrides using diphenyl carbonate based on activation of α-amino acids by converting into imidazolium salts
Koga, Koichi,Sudo, Atsushi,Endo, Takeshi
experimental part, p. 4351 - 4355 (2011/11/30)
The phosgene-free synthesis of α-amino acid n-carboxyanhydrides using diphenyl carbonate based on activation of α-amino acids by converting into imidazolium salts was reported. 1-Ethyl-3-methylimidazolium bromide (4.77 g, 25.0 mmol) was dissolved in water (25 mL) and was passed through a column of Amberlite IRA 400 CL (50 cm3) using 250 mL of water as an eluent to synthesize amino acid imidazolium salt. A solution of L-phenylalanine imidazolium salt (550 mg, 2.0 mmol) in acetonitrile (15 mL) was added dropwise to a solution of diphenyl-carbonate (427 mg, 2.00 mmol) in acetonitrile (5 mL) at room temperature, and the reaction mixture was stirred at room temperature to synthesize urethane derivative. The results showed that all of the obtained imidazolium salts were soluble in chloroform, dichloromethane, 2-butanone acetonitrile, and not soluble in tetrahydrofuran.
