56438-69-8

Basic information

• Product Name: 1-Butanone, 1-(1,3-benzodioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)-
• CAS NO: 56438-69-8
• Molecular Formula: C20H22O6
• Molecular Weight: 358.391
• Mol File: 56438-69-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(1,3-benzodioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(1,3-benzodioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)-(56438-69-8)
• EPA Substance Registry System: 1-Butanone, 1-(1,3-benzodioxol-5-yl)-4-(3,4,5-trimethoxyphenyl)-(56438-69-8)

Safety Data

• Hazardous Substances Data: 56438-69-8(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 25245-29-8 5-iodo-1,2,3-trimethoxybenzene 
• 42337-03-1 1-benzo[1,3]dioxol-5-yl-but-3-en-1-ol 
• 56438-67-6 1-(6-Bromo-benzo[1,3]dioxol-5-yl)-4-(2-iodo-3,4,5-trimethoxy-phenyl)-butan-1-one 

Relevant articles and documents

Chemoenzymatic Total Synthesis of Deoxy-, epi-, and Podophyllotoxin and a Biocatalytic Kinetic Resolution of Dibenzylbutyrolactones

Podophyllotoxin is probably the most prominent representative of lignan natural products. Deoxy-, epi-, and podophyllotoxin, which are all precursors to frequently used chemotherapeutic agents, were prepared by a stereodivergent biotransformation and a biocatalytic kinetic resolution of the corresponding dibenzylbutyrolactones with the same 2-oxoglutarate-dependent dioxygenase. The reaction can be conducted on 2 g scale, and the enzyme allows tailoring of the initial, “natural” structure and thus transforms various non-natural derivatives. Depending on the substitution pattern, the enzyme performs an oxidative C?C bond formation by C?H activation or hydroxylation at the benzylic position prone to ring closure.