566-01-8

Basic information

• Product Name: 5B-PREGNANE-11B,21-DIOL-3,20-DIONE
• Synonyms: 5B-PREGNANE-11B,21-DIOL-3,20-DIONE;5B-Dihydrocorticosterone;11β,21-Dihydroxy-5β-pregnane-3,20-dione;5β-Dihydrocorticosterone, 5β-Pregnane-11β,21-diol-3,20-dione;(5R,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
• CAS NO: 566-01-8
• Molecular Formula: C21H32O4
• Molecular Weight: 348.47638
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 566-01-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 508.5°Cat760mmHg
• Flash Point: 275.4°C
• Appearance: /
• Density: 1.175g/cm³
• Vapor Pressure: 1.82E-12mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Sparingly), Dichloromethane (Slightly)
• CAS DataBase Reference: 5B-PREGNANE-11B,21-DIOL-3,20-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5B-PREGNANE-11B,21-DIOL-3,20-DIONE(566-01-8)
• EPA Substance Registry System: 5B-PREGNANE-11B,21-DIOL-3,20-DIONE(566-01-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 566-01-8(Hazardous Substances Data)

Usage

Description

5B-PREGNANE-11B,21-DIOL-3,20-DIONE, also known as 5β-dihydrocorticosterone, is a steroid hormone derivative that belongs to the pregnane family. It is characterized by its unique molecular structure, which includes a pregnane core with a 5β-configuration, an 11β,21-diol substitution, and a 3,20-dione functional group. 5B-PREGNANE-11B,21-DIOL-3,20-DIONE has been identified for its potential biological activities and applications in various fields.

Uses

Used in Pharmaceutical Industry:
5B-PREGNANE-11B,21-DIOL-3,20-DIONE is used as a pharmaceutical compound for its potential therapeutic effects. It has been found in the exudate of granuloma after corticosteroid intravenous administration, suggesting that it may play a role in the body's response to inflammation and immune system regulation. Further research and development could lead to the discovery of new treatments for various medical conditions.
Used in Research and Development:
In the field of research and development, 5B-PREGNANE-11B,21-DIOL-3,20-DIONE serves as a valuable compound for studying the structure-activity relationships of steroid hormones and their derivatives. Its unique molecular structure and biological activities make it an interesting subject for further investigation, which could potentially lead to the development of novel drugs and therapies.
Used in Analytical Chemistry:
5B-PREGNANE-11B,21-DIOL-3,20-DIONE can also be used as a reference compound in analytical chemistry for the development and validation of analytical methods for the detection and quantification of steroid hormones and their metabolites. Its unique structural features make it a suitable candidate for the establishment of calibration curves and the assessment of method performance.

InChI:InChI=1/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12,14-17,19,22,24H,3-11H2,1-2H3

Downstream Products

• 27857-26-7 3β.11β.21-trihydroxy-5β-pregnanone-(20)