56653-43-1

Basic information

• Product Name: 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE
• Synonyms: 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE;2-broMo-1-(1-Methyl-1H-benzo[d]iMidazol-2-yl)ethanone;2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)ethanone
• CAS NO: 56653-43-1
• Molecular Formula: C₁₀H₉BrN₂O
• Molecular Weight: 253.1
• Mol File: 56653-43-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 100 °C
• Boiling Point: 371.9°Cat760mmHg
• Flash Point: 178.7°C
• Appearance: /
• Density: 1.57g/cm³
• Vapor Pressure: 9.96E-06mmHg at 25°C
• Refractive Index: 1.65
• PKA: 2.99±0.10(Predicted)
• CAS DataBase Reference: 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE(56653-43-1)
• EPA Substance Registry System: 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE(56653-43-1)

Safety Data

• Hazardous Substances Data: 56653-43-1(Hazardous Substances Data)

Usage

General Description

2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE is a chemical compound with the molecular formula C11H10BrNO. It is a yellow solid with a molecular weight of 258.11 g/mol. 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE is primarily used in chemical research and drug development, as it possesses potential pharmaceutical properties. It is known to inhibit certain enzymes and has shown promise in various biological studies. Additionally, it is also used in the synthesis of other organic compounds. However, caution should be exercised when handling 2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE due to its potential hazardous nature and the need for proper handling and disposal procedures.

InChI:InChI=1/C10H9BrN2O/c1-13-8-5-3-2-4-7(8)12-10(13)9(14)6-11/h2-5H,6H2,1H3

Upstream product

• 942-25-6 2-acetyl-1-methylbenzimidazole 
• 939-70-8 2-acetylbenzimidazole 
• 16414-04-3 1-benzimidazol-2-ylethanol 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 243668-28-2 1-(1-methyl-1H-benzo[d]imidazol-2-yl)-2-(phenylthio)ethanone 
• 1210527-97-1 2-iodobenzoic acid 2-(1-methyl-1H-benzimidazol-2-yl)-2-oxoethyl ester 
• 1210527-99-3 2-(1-methyl-1H-benzimidazol-2-yl)-2-oxoethyl 4-cyanobenzoate 
• 1210528-01-0 3-trifluoromethylbenzoic acid 2-(1-methyl-1H-benzimidazol-2-yl)-2-oxoethyl ester 
• 566930-39-0 2-(1-methyl-1H-benzimidazol-2-yl)-2-oxoethyl benzoate 
• 1591908-03-0 4-(1-methyl-1H-benzimidazol-2-yl)-3-(phenylsulfonyl)pyrazolo[5,1-c][1,2,4]triazine-8-carbonitrile 
• 1591908-02-9 7-(4-chlorophenyl)-4-(1-methyl-1H-benzimidazol-2-yl)-3-(phenylsulfonyl)pyrazolo[5,1-c][1,2,4]triazine 
• 1591908-25-6 4-(1-methylbenzimidazol-2-yl)-5-cyano-1,6-dihydro-6-imin-3-(phenylsulfonyl)-1-(4-methylphenyl)pyridazine 
• 1591908-24-5 4-(1-methylbenzimidazol-2-yl)-5-cyano-1,6-dihydro-6-imin-3-(phenylsulfonyl)-1-(4-chlorophenyl)pyridazine 
• 1591908-23-4 4-(1-methylbenzimidazol-2-yl)-5-cyano-1,6-dihydro-6-imino-3-(phenylsulfonyl)-1-(phenyl)pyridazine 
• 1591908-19-8 5-(benzothiazol-2-yl)-1,6-dihydro-6-imino-3-(1-methylbenzimidazol-2-yl)-3-(phenylsulphonyl)-1-(4-methylphenyl)pyridazine 
• 1591908-18-7 5-(benzothiazol-2-yl)-1,6-dihydro-6-imino-3-(1-methylbenzimidazol-2-yl)-3-(phenylsulphonyl)-1-(4-chlorophenyl)pyridazine 
• 1591908-17-6 5-(benzothiazol-2-yl)-1,6-dihydro-6-imino-3-(1-methylbenzimidazol-2-yl)-3-(phenylsulphonyl)-1-(phenyl)pyridazine 
• 1591908-13-2 1-(1-methyl-1H-benzimidazol-2-yl)-2-(phenylsulfonyl)-2-(2-p-tolylhydrazono)ethanone 

Relevant articles and documents

Synthesis of Some Benzimidazole-based Heterocycles and their Application as Copper Corrosion Inhibitors

A series of new substituted benzimidazoles embedded with a variety of function groups has been synthesized from N-methyl-2-bromoacetylbenzimidazole. The synthesized compounds were fully characterized, and their structures were elucidated based on elemental analysis, spectral data, and alternative synthetic pathways, whenever possible. Some of benzimidazole derivatives were tested as corrosion inhibitors.

Facile and simple synthesis of novel 1-Methyl-2-(2-substituted-oxazol-4-yl) -1H-benzimidazole derivatives

Novel 1-methyl-2-(2-substituted-oxazol-4-yl)-1H-benzimidazole derivatives were obtained in good yields and purity by treating corresponding 2-benzimidazolyl esters with acetamide in the presence of BF3- etherate, a Lewis acid.

One-pot synthesis of 2-(1-alkyl/aralkyl-1H-benzimidazole-2-yl)-quinoxaline derivatives using molecular iodine

The title compound (5) has been prepared in one pot by refluxing 1-(1-alkyl/aralkyl-1H-benzimidazole-2-yl)-ethanone (1) with substituted o-phenylenediamine (2) in ethanol in the presence of iodine. Alternatively, 5 could also be prepared by treating 2-bromo-1-(1- alkyl/aralkyl-1H-benzimidazole- 2-yl)-ethanone (3A) with 2 in refluxing ethanol. The formation of 5 from 1 and 2 probably occurs through the intermediacy of 3B (i.e., 3, X=I) and 4. Copyright Taylor & Francis Group, LLC.