5667-75-4

Basic information

• Product Name: ethyl 2-phenyl-2-(p-tolylamino)acetateacetate
• Synonyms: ethyl 2-phenyl-2-(p-tolylamino)acetateacetate
• CAS NO: 5667-75-4
• Molecular Weight: 269.343
• Mol File: 5667-75-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 2-phenyl-2-(p-tolylamino)acetateacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-phenyl-2-(p-tolylamino)acetateacetate(5667-75-4)
• EPA Substance Registry System: ethyl 2-phenyl-2-(p-tolylamino)acetateacetate(5667-75-4)

Safety Data

• Hazardous Substances Data: 5667-75-4(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 22065-57-2 ethyl 2-phenyldiazoacetate 
• 101-97-3 Ethyl 2-phenylethanoate 

Downstream Products

• 93-89-0 benzoic acid ethyl ester 

Relevant articles and documents

Method for realizing insertion reaction of diazo ester compound and aniline molecule N-H through photocatalytic micro-channel

A homogeneous solution containing the aniline represented by the formula N, a derivative thereof and a diazo ester compound shown H is pumped into a microchannel reaction device with a light source to react to obtain I phenyl II benzene ethyl acetate deri

Carbene X[sbnd]H bond insertions catalyzed by copper(I) macrocyclic pyridine-containing ligand (PcL) complexes

A catalytic system comprising copper(I) and macrocyclic pyridine-containing ligands (Pc-L) proves capable of promoting carbene Si[sbnd]H bond insertions using diazo compounds as the carbene source. This catalytic system showed broad scope and a remarkable robustness as indicated by high TON numbers (up to 30000). Moreover, the use of enynones as carbene sources proved also feasible in hydrosilane insertion using this catalytic system. Finally, the insertion in O[sbnd]H and N[sbnd]H bonds of phenols and anilines, respectively, has been also demonstrated.

Palladium-catalyzed carbenoid based N-H bond insertions: Application to the synthesis of chiral α-amino esters

A highly efficient palladium-catalyzed carbenoid based N-H bond insertion has been developed. The α-amino esters were obtained in high isolated yields. Moreover, by choosing a suitable chiral auxiliary, stereoselective Pd-catalyzed N-H insertion has been realized. The chiral α-amino esters were obtained in high yields (up to 91%) and with excellent diastereoselectivities (d.r. > 19:1). The Royal Society of Chemistry.