566944-05-6 Usage
General Description
N-(6-isoquinolinyl)acetamide is a chemical compound with the molecular formula C11H10N2O that is also known as isoquinolinylacetamide. It is a member of the acetamide class of compounds and contains a unique isoquinoline ring structure. This chemical has potential applications in pharmaceutical research, particularly in the development of new drugs and treatments. It may also be used as a building block in organic synthesis and medicinal chemistry. N-(6-isoquinolinyl)acetamide should be handled and used with caution due to its potential for biological activity and toxicity. Additional research and testing are warranted to fully understand the properties and potential uses of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 566944-05-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,6,9,4 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 566944-05:
(8*5)+(7*6)+(6*6)+(5*9)+(4*4)+(3*4)+(2*0)+(1*5)=196
196 % 10 = 6
So 566944-05-6 is a valid CAS Registry Number.
566944-05-6Relevant articles and documents
Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors
Chen, Ping,Norris, Derek,Haslow, Kristin D.,Dhar, T. G. Murali,Pitts, William J.,Watterson, Scott H.,Cheney, Daniel L.,Bassolino, Donna A.,Fleener, Catherine A.,Rouleau, Katherine A.,Hollenbaugh, Diane L.,Townsend, Robert M.,Barrish, Joel C.,Iwanowicz, Edwin J.
, p. 1345 - 1348 (2003)
Screening of our in-house compound collection led to the discovery of 5-bromo-6-amino-2-isoquinoline 1 as a weak inhibitor of IMPDH. Subsequent optimization of 1 afforded a series of novel 2-isoquinolinoaminooxazole-based inhibitors, represented by 17, with single-digit nanomolar potency against the enzyme.
