56695-65-9

Basic information

• Product Name: ROSAPROSTOL
• Synonyms: ROSAPROSTOL;AY-22469;C-83;IBI-C83;Rosal;Einecs 260-341-8;Rosaprostolum;Rosaprostolum [latin]
• CAS NO: 56695-65-9
• Molecular Formula: C₁₈H₃₄O₃
• Molecular Weight: 298.464
• EINECS: 260-341-8
• Mol File: 56695-65-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 442.1°C at 760 mmHg
• Flash Point: 235.3°C
• Appearance: /
• Density: 0.981g/cm³
• Vapor Pressure: 1.13E-09mmHg at 25°C
• Refractive Index: 1.481
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: ROSAPROSTOL(CAS DataBase Reference)
• NIST Chemistry Reference: ROSAPROSTOL(56695-65-9)
• EPA Substance Registry System: ROSAPROSTOL(56695-65-9)

Safety Data

• Hazardous Substances Data: 56695-65-9(Hazardous Substances Data)

Usage

Description

Rosaprostol, also known by its brand name ROSAL, is an antisecretory and cytoprotective prostaglandin analog that is primarily used in the treatment of gastric and duodenal ulcers. It is considerably less potent than other prostaglandin analogs such as enprostil or misoprostol, but it is also reported to lack the typical gastrointestinal and cardiovascular side effects associated with PGE derivatives.

Uses

Used in Pharmaceutical Industry:
Rosaprostol is used as a therapeutic agent for the treatment of gastric and duodenal ulcers. Its antisecretory and cytoprotective properties help in reducing the severity of ulcers and promoting healing. Additionally, its lower potency compared to other prostaglandin analogs results in fewer gastrointestinal and cardiovascular side effects, making it a safer option for patients.
Used in Gastroenterology:
In the field of gastroenterology, Rosaprostol is used as a medication to alleviate the symptoms of gastric and duodenal ulcers. Its ability to reduce the secretion of gastric acid and protect the stomach lining makes it an effective treatment option for patients suffering from these conditions.

Originator

Inatituto Biochemico Italiano (Italy)

InChI:InChI=1/C18H34O3/c1-2-3-4-7-10-15-13-14-17(19)16(15)11-8-5-6-9-12-18(20)21/h15-17,19H,2-14H2,1H3,(H,20,21)/t15-,16+,17?/m0/s1

Upstream product

• 59659-94-8 7-(2-hexyl-5-keto-cyclopentyl)-heptanoic acid 

Relevant articles and documents

Process for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid

A multistep process for preparing 7-(2-hexyl-5-hydroxy-cyclopentyl)-heptanoic acid is described. Novel intermediates are also described.