56716-92-8

Basic information

• Product Name: 7-BROMO-2-METHYL-4-QUINOLINOL
• Synonyms: 7-BROMO-2-METHYL-4-QUINOLINOL;7-Bromo-4-hydroxy-2-methylquinoline;7-broMo-2-Methylquinolin-4-ol;NSC 366402;7-bromo-2-methyl-1H-quinolin-4-one
• CAS NO: 56716-92-8
• Molecular Formula: C10H8BrNO
• Molecular Weight: 238.0806
• Mol File: 56716-92-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 324.6°Cat760mmHg
• Flash Point: 150.1°C
• Appearance: /
• Density: 1.523g/cm³
• Vapor Pressure: 0.000244mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 7-BROMO-2-METHYL-4-QUINOLINOL(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-2-METHYL-4-QUINOLINOL(56716-92-8)
• EPA Substance Registry System: 7-BROMO-2-METHYL-4-QUINOLINOL(56716-92-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 56716-92-8(Hazardous Substances Data)

Usage

General Description

7-Bromo-2-methyl-4-quinolinol, also known as broxyquinoline, is a chemical compound with the molecular formula C10H8BrNO. It is a derivative of the quinolinol family and is commonly used as an antifungal agent and biocide. 7-BROMO-2-METHYL-4-QUINOLINOL is known for its ability to inhibit the growth of various fungi and has been used in a wide range of industrial and agricultural applications. It is also used as a corrosion inhibitor and has potential applications in the pharmaceutical and polymer industries. 7-Bromo-2-methyl-4-quinolinol is considered to be a moderately hazardous chemical and should be handled with appropriate care and safety measures.

InChI:InChI=1/C10H8BrNO/c1-6-4-10(13)8-3-2-7(11)5-9(8)12-6/h2-5H,1H3,(H,12,13)

Upstream product

• 1374869-13-2 7-bromo-4-hydroxy-2-methylquinoline-3-carboxylic acid 
• 1374869-12-1 ethyl 7-bromo-4-hydroxy-2-methylquinoline-3-carboxylate 
• 1374869-11-0 diethyl 2-(1-(3-bromophenylamino)ethylidene)malonate 
• 591-19-5 m-Bromoaniline 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 1445879-70-8 3-((3-(N-cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)-2-methylquinolin-4-yl)amino)-5-isopropoxybenzoic acid 
• 1445880-75-0 methyl 3-(3-(N-cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)-2-methylquinolin-4-ylamino)-5-isopropoxybenzoate 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention is directed to substituted quinoline derivatives. Specifically, the invention is directed to compounds according to Formula I: wherein R, R1, R2, R3 and R4 are defined herein. The compounds of the invention are inhibitors of lactate dehydrogenase A and can be useful in the treatment of cancer and diseases associated with tumor cell metabolism, such as cancer, and more specifically cancers of the breast, colon, prostate and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting lactate dehydrogenase A activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.