56767-37-4

Basic information

• Product Name: N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE
• Synonyms: N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE;PROPANAMIDE, 3-CHLORO-N-(4-FLUOROPHENYL)-;3-CHLORO-N-(4-FLUOROPHENYL)PROPANAMIDE;AKOS BBS-00000716
• CAS NO: 56767-37-4
• Molecular Formula: C9H9ClFNO
• Molecular Weight: 201.63
• Mol File: 56767-37-4.mol
• Article Data: 8

Chemical Properties

• Melting Point: 120-122°C
• Appearance: /
• CAS DataBase Reference: N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE(56767-37-4)
• EPA Substance Registry System: N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE(56767-37-4)

Safety Data

• Hazardous Substances Data: 56767-37-4(Hazardous Substances Data)

Usage

Description

N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE, also known as 3-chloro-N-(4-fluorophenyl)propanamide, is an organic compound that serves as a valuable reactant in the synthesis of various chemical compounds. It is characterized by the presence of a chloro group, a fluorophenyl group, and a propanamide group in its molecular structure.

Uses

Used in Pharmaceutical Industry:
N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE is used as a reactant for the synthesis of 5,5-diphenylimidazolidine-2,4-dione derivatives, which have been studied for their anti-inflammatory and analgesic activities. These derivatives have potential applications in the development of new drugs for the treatment of pain and inflammation.
Used in Chemical Synthesis:
N-(4-FLUOROPHENYL)-3-CHLOROPROPANAMIDE is used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure allows for the formation of diverse chemical entities with potential applications in different industries.

Upstream product

• 625-36-5 2-chloropropionyl chloride 
• 371-40-4 4-fluoroaniline 

Relevant articles and documents

Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model

Histone deacetylase 6 (HDAC6) is a promising therapeutic target for the treatment of neurodegenerative disorders. SW-100 (1a), a phenylhydroxamate-based HDAC6 inhibitor (HDAC6i) bearing a tetrahydroquinoline (THQ) capping group, is a highly potent and sel

TETRAHYDROQUINOLINE SUBSTITUTED HYDROXAMIC ACIDS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS

Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, tr

Synthesis of some 1,2,4-triazoles as potential anti-tubercular agents

A series of 5-(N-substituted carboxamidoethylthio)-3-(3'pyridyl)-4- amino-1,2,4-triazole derivatives 6a-j have been synthesized and evaluated for anti-tubercular activity. They are screened in-vitro at 10μg/mL concentration against Mycobacterium tuberculosis H37RV (ATCC 27294). All the compounds are showing antitubercular activity when compared with the standard drug Amikacin. Compounds 6e and 6h are found active as they displayed IC50 and IC90 values at 100μg/mL.