56812-60-3 Usage
General Description
2-Bromobenzylmagnesium bromide is a chemical compound consisting of a benzene ring that is substituted with a bromine atom and a magnesium atom bonded to the benzyl group. It is a versatile organometallic reagent commonly used in organic synthesis as a Grignard reagent, reacting with various electrophiles such as halides, carbonyl compounds, and epoxides to form new carbon-carbon bonds. This reagent is particularly useful in the formation of carbon-carbon bonds and is widely employed in the synthesis of complex organic molecules and pharmaceuticals. Additionally, it has been utilized in the preparation of various natural products, bioactive compounds, and advanced materials due to its high reactivity and functional group tolerance.
Check Digit Verification of cas no
The CAS Registry Mumber 56812-60-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,8,1 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 56812-60:
(7*5)+(6*6)+(5*8)+(4*1)+(3*2)+(2*6)+(1*0)=133
133 % 10 = 3
So 56812-60-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Br.BrH.Mg/c1-6-4-2-3-5-7(6)8;;/h2-5H,1H2;1H;/q-1;;+2/p-1
56812-60-3Relevant articles and documents
Benzylic Grignard Reagents: Application of (thf = tetrahydrofuran) in Regioselective Grignard Formation and C-O Cleavage in Benzyl Ethers
Gallagher, Michael J.,Harvey, Stephen,Raston, Colin L.,Sue, Rodney E.
, p. 289 - 290 (2007/10/02)
Benzylic Grignard reagents (2)-(4), bearing ortho- and para-halogeno ring substituents, are readily accessible by treating the corresponding benzylic halide with (1) in tetrahydrofuran (thf); o- and p-chloromethyl(methoxymethyl)benzenes with (1) rapidly yield 'di-Grignards' whereas the meta-isomer only affords a mono-Grignard' (5), and bis(methoxymethyl)benzenes slowly undergo C-O cleavage, (6).
