56857-02-4

Basic information

• Product Name: 1,3-Dioxolane, 2-(3-bromo-2-thienyl)-
• CAS NO: 56857-02-4
• Molecular Formula: C7H7BrO2S
• Molecular Weight: 235.101
• Mol File: 56857-02-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane, 2-(3-bromo-2-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane, 2-(3-bromo-2-thienyl)-(56857-02-4)
• EPA Substance Registry System: 1,3-Dioxolane, 2-(3-bromo-2-thienyl)-(56857-02-4)

Safety Data

• Hazardous Substances Data: 56857-02-4(Hazardous Substances Data)

Usage

Description

1,3-Dioxolane, 2-(3-bromo-2-thienyl)is a heterocyclic organic compound with the molecular formula C6H7BrO2S. It consists of a dioxolane ring and a thienyl group, and is characterized as a colorless liquid with a strong, unpleasant odor.
Used in Organic Synthesis:
1,3-Dioxolane, 2-(3-bromo-2-thienyl)is used as a reagent in organic synthesis for its ability to facilitate various chemical reactions and contribute to the formation of complex organic molecules.
Used in Chemical Reactions as a Solvent:
1,3-Dioxolane, 2-(3-bromo-2-thienyl)serves as a solvent in a range of chemical reactions, providing a medium that allows for the effective mixing and interaction of reactants, thus promoting desired chemical transformations.
Used in Formulation Stabilization:
1,3-Dioxolane, 2-(3-bromo-2-thienyl)is utilized as a stabilizer in certain formulations to maintain the consistency, effectiveness, and safety of the final product over time.
Used in Research and Development for Pharmaceutical Applications:
Due to its unique chemical structure, 1,3-Dioxolane, 2-(3-bromo-2-thienyl)is explored in research and development for potential uses in the pharmaceutical industry, where it may contribute to the creation of new drugs or drug delivery systems.
Used in Research and Development for Agrochemical Applications:
Similarly, this compound is also being investigated for its potential in agrochemical applications, where it could be used to develop new pesticides, herbicides, or other agricultural chemicals.
It is crucial to handle 1,3-Dioxolane, 2-(3-bromo-2-thienyl)with care, as it is a potential irritant to the skin, eyes, and respiratory system, requiring proper safety measures during its use and manipulation.

Upstream product

• 930-96-1 3-bromo-2-thiophenecarboxaldehyde 
• 104-15-4 toluene-4-sulfonic acid 
• 107-21-1 ethylene glycol 

Downstream Products

• 31486-86-9 thieno[3,2-b]thiophene-2-carbaldehyde 
• 1394824-47-5 C₁₄H₁₁NS 

Relevant articles and documents

HISTONE ACETYLTRANSFERASE (HAT) INHIBITOR AND USE THEREOF

The present invention relates to a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising the same, and use thereof in the treatment of various HAT-related diseases or conditions.

Synthesis of 4-thiophen-2′-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel

The gating of the CFTR chloride channel is altered by a group of mutations that cause cystic fibrosis. This gating defect may be corrected by small molecules called potentiators. Some 1,4-dihydropyridine (DHP) derivatives, bearing a thiophen-2-yl and a furanyl ring at the 4-position of the nucleus, were prepared and tested as CFTR potentiators. In particular, we evaluated the ability of novel DHPs to enhance the activity of the rescued ΔF508-CFTR as measured with a functional assay based on the halide-sensitive yellow fluorescent protein. Most DHPs showed an effect comparable to or better than that of the reference compound genistein. The potency was instead significantly improved, with some compounds, such as 3g, 3h, 3n, 4a, 4b, and 4d, having a half effective concentration in the submicromolar range. CoMFA analysis gave helpful suggestions to improve the activity of DHPs.

Oxaboroles and salts thereof, and their use as biocides

A method for the protection of a medium by susceptible to microbial attack by the treatment of the medium with an oxaborale or a salt of an oxaborale.