568570-13-8 Usage
Also known as
Lamivudine
Type
Synthetic nucleoside analogue
Antiviral properties
Uses
Treatment of HIV and hepatitis B infections
Mechanism of action
Inhibits the reverse transcriptase enzyme
Reduces viral load in the body
Slows down disease progression
Administration
Oral
Tolerance
Generally well-tolerated
Common side effects
Nausea, headache, fatigue
Component of combination antiretroviral therapy for HIV management
First-line treatment for chronic hepatitis B
Check Digit Verification of cas no
The CAS Registry Mumber 568570-13-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,8,5,7 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 568570-13:
(8*5)+(7*6)+(6*8)+(5*5)+(4*7)+(3*0)+(2*1)+(1*3)=188
188 % 10 = 8
So 568570-13-8 is a valid CAS Registry Number.
568570-13-8Relevant articles and documents
Synthesis and antiviral activity of benzimidazolyl-and triazolyl-1,3,5- triazines
Maarouf, Azza R.,Farahat, Abdelbasset A.,Selim, Khalid B.,Eisa, Hassan M.
, p. 703 - 710 (2012/09/22)
A novel series of 1,3,5-triazine analogs was successfully synthesized through conjugation with benzimidazole or 1,2,4-triazole derivatives via a methylenethio linker. The new analogs were in vitro evaluated against HSV-1 in Vero cells; among these analogs, two compounds exhibited good effect in inhibiting HSV-1 replication (for compound 5p: EC50 = 3.5 μg/ml, SI = 358; for compound 5r: EC50 = 5.0 μg/ml, SI = 300) in comparison to acyclovir. Springer Science+Business Media, LLC 2011.
