56882-77-0

Basic information

• Product Name: 4-thiadiazole,2-amino-5-cyclohexyl-3
• Synonyms: 2-amino-5-cicloesil-1,3,4-tiadiazolo;4-thiadiazole,2-amino-5-cyclohexyl-3;1,3,4-Thiadiazole, 2-amino-5-cyclohexyl-;2-Amino-5-cicloesil-1,3,4-tiadiazolo [Italian]
• CAS NO: 56882-77-0
• Molecular Formula: C₈H₁₃N₃S
• Molecular Weight: 183.278
• Mol File: 56882-77-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 343.8°C at 760 mmHg
• Flash Point: 161.7°C
• Appearance: /
• Density: 1.231g/cm³
• Vapor Pressure: 6.86E-05mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 4-thiadiazole,2-amino-5-cyclohexyl-3(CAS DataBase Reference)
• NIST Chemistry Reference: 4-thiadiazole,2-amino-5-cyclohexyl-3(56882-77-0)
• EPA Substance Registry System: 4-thiadiazole,2-amino-5-cyclohexyl-3(56882-77-0)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• HazardClass: IRRITANT
• Hazardous Substances Data: 56882-77-0(Hazardous Substances Data)

Usage

General Description

4-thiadiazole,2-amino-5-cyclohexyl-3 is a chemical compound with the molecular formula C8H12N4S. It belongs to the group of heterocyclic compounds, specifically 1,3,4-thiadiazoles, which are known for their diverse biological activities. This particular compound has a cyclohexyl group attached to the amino group in the 2-position of the thiadiazole ring. It has shown potential pharmacological and medicinal properties, including antimicrobial, antifungal, and anti-inflammatory activities. It also has potential applications in the development of drugs and pharmaceuticals due to its unique structure and biological properties. Research on this compound continues to explore its potential uses and benefits in various fields.

InChI:InChI=1/C8H13N3S/c9-8-11-10-7(12-8)6-4-2-1-3-5-6/h6H,1-5H2,(H2,9,11)

Upstream product

• 79-19-6 thiosemicarbazide 
• 2043-61-0 cyclohexanecarbaldehyde 
• 255715-64-1 2-(cyclohexylmethylidene)hydrazinecarbothioamide 
• 98-89-5 Cyclohexanecarboxylic acid 
• 2719-27-9 cyclohexanylcarbonyl chloride 

Downstream Products

• 1000383-56-1 C₁₇H₁₆ClN₃OS 
• 1000383-57-2 C₁₈H₁₉N₃OS 
• 1000383-58-3 C₁₈H₁₉N₃O₂S 
• 497079-04-6 1-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-3-(3,4-dichlorophenyl)urea 
• 879859-60-6 2-cyclohexyl-6-(4-bromophenyl)imidazo[2,1-b][1,3,4]thiadiazole 
• 105613-25-0 2-Bromo-5-cyclohexyl-1,3,4-thiadiazole 
• 83390-43-6 3-cyclohexyl-6,8-dibromo-2--4(3H)-quinazolone 
• 83390-37-8 N-(5-Cyclohexyl-[1,3,4]thiadiazol-2-yl)-2-[6,8-dibromo-3-(2-ethyl-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetamide 
• 83390-39-0 N-(5-Cyclohexyl-[1,3,4]thiadiazol-2-yl)-2-[6,8-dibromo-3-(4-methoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-acetamide 
• 83390-34-5 6-bromo-3-cyclohexyl-2--4(3H)-quinazolone 
• 83390-36-7 N-(5-Cyclohexyl-[1,3,4]thiadiazol-2-yl)-2-(6,8-dibromo-4-oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetamide 
• 83390-29-8 2-[6-Bromo-3-(2-ethyl-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl]-N-(5-cyclohexyl-[1,3,4]thiadiazol-2-yl)-acetamide 
• 83390-41-4 2-(3-Benzyl-6,8-dibromo-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-N-(5-cyclohexyl-[1,3,4]thiadiazol-2-yl)-acetamide 

Relevant articles and documents

Novel 1,3,4-thiadiazole conjugates derived from protocatechuic acid: Synthesis, antioxidant activity, and computational and electrochemical studies

A series of 15 novel 1,3,4-thiadiazole amide derivatives containing a protocatechuic acid moiety were synthesized and structurally characterized. In addition, the corresponding imino (4) and amino (5) analogues of a phenyl-substituted 1,3,4-thiadiazole am

Synthesis and evaluation of novel 1,3,4-thiadiazole–fluoroquinolone hybrids as antibacterial, antituberculosis, and anticancer agents

A series of 5-substituted-1,3,4-thiadiazole-based fluoroquinolone derivatives were designed as potential antibacterial and anticancer agents using a molecular hybridization approach. The target compounds 16–25 were synthesized by reacting the correspondin

Thiadiazole derivatives active on the central nervous system and pharmaceutical compositions

The invention relates to thiadiazole derivatives corresponding to the formula: STR1 in which R represents: a linear or branched alkyl group having from 1 to 5 carbon atoms; a cycloalkyl group having 5 or 6 carbon atoms; a phenyl group optionally substitut