5689-33-8 Usage
Description
3-(Cyanomethyl)benzoic Acid, a chemical compound with the formula C8H5NO2, is an organic compound that features a benzoic acid structure with a cyanomethyl group attached to the third carbon. It is known for its role in the synthesis of various pharmaceutically important compounds due to its unique chemical properties.
Uses
Used in Pharmaceutical Synthesis:
3-(Cyanomethyl)benzoic Acid is used as a reagent for the synthesis of various pharmaceutically important compounds. Its application in the pharmaceutical industry is primarily due to its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in the Synthesis of Neprilysin Inhibitors:
Specifically, 3-(Cyanomethyl)benzoic Acid is utilized in the synthesis of neprilysin inhibitors. Neprilysin is an enzyme that breaks down certain neurotransmitters and peptides in the body. Inhibiting this enzyme can have therapeutic effects in treating conditions such as Alzheimer's disease, where maintaining the levels of certain neurotransmitters is crucial for managing the symptoms.
Check Digit Verification of cas no
The CAS Registry Mumber 5689-33-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,8 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5689-33:
(6*5)+(5*6)+(4*8)+(3*9)+(2*3)+(1*3)=128
128 % 10 = 8
So 5689-33-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO2/c10-5-4-7-2-1-3-8(6-7)9(11)12/h1-3,6H,4H2,(H,11,12)
5689-33-8Relevant articles and documents
Ligand-Free Palladium-Catalyzed Hydroxycarbonylation of Aryl Halides under Ambient Conditions: Synthesis of Aromatic Carboxylic Acids and Aromatic Esters
Han, Wei,Jin, Fengli,Zhou, Qing
, p. 1861 - 1868 (2015/06/30)
Aryl halides were readily converted into their corresponding aromatic carboxylic acids in high yields with high selectivity by ligand-free palladium-catalyzed hydroxycarbonylation at room temperature and atmospheric pressure. The new method is operationally simple and scalable. In addition, aromatic esters were easily synthesized through one-pot hydroxycarbonylation/alkylation with alkyl halides.
USE OF DERIVATIVES OF 2, 4-DIHYDRO-[1,2,4]TRIAZOLE-3-THIONE AS INHIBITORS O FTEH ENZYME MYELOPEROXIDASE (MPO)
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Page 80, (2010/02/09)
There is disclosed the use of a compound of formula (I) wherein X, Y, W and Q are as defined in the specification, and pharmaceutically acceptable salts thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of the enzyme myeloperoxidase (MPO) is beneficial. Certain novel compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed, together with processes for their preparation. The compounds of formulae (I) are MPO inhibitors and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders.
