569352-00-7Relevant articles and documents
Solid phase peptide templated glycosidic bond formation
Tennant-Eyles, Richard J.,Davis, Benjamin G.,Fairbanks, Antony J.
, p. 1201 - 1210 (2007/10/03)
Glycosylation reactions performed between a glycosyl donor and acceptor covalently linked to a peptide template both in the solution and solid phase give similar yields and product distributions. The adoption of a solid phase approach opens the way for the synthesis of libraries of peptide templates in an attempt to screen for particular peptide sequences that effect complete regio-and stereochemical control during glycosidic bond formation, whilst the use of second generation donors allows the possibility of an iterative approach.