569656-77-5

Basic information

• Product Name: Acetic acid, [(5S)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1-[(4-methylphenyl) sulfonyl]-3-pyrrolidinylidene]-, ethyl ester
• CAS NO: 569656-77-5
• Molecular Formula: C32H39NO5SSi
• Molecular Weight: 577.817
• Mol File: 569656-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(5S)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1-[(4-methylphenyl) sulfonyl]-3-pyrrolidinylidene]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(5S)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1-[(4-methylphenyl) sulfonyl]-3-pyrrolidinylidene]-, ethyl ester(569656-77-5)
• EPA Substance Registry System: Acetic acid, [(5S)-5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-1-[(4-methylphenyl) sulfonyl]-3-pyrrolidinylidene]-, ethyl ester(569656-77-5)

Safety Data

• Hazardous Substances Data: 569656-77-5(Hazardous Substances Data)

Upstream product

• 569656-76-4 (3R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidin-3-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 57850-05-2 (2S,4R)-2-Hydroxymethyl-4-hydroxy-1-(4-toluenesulfonyl)-pyrrolidine 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 569656-60-6 (5S)-(5-tert-butyldiphenylsilyloxymethyl)-1-(toluene-4-sulfonyl)pyrrolidin-3-one 

Downstream Products

• 569656-65-1 (2S)-[2-(toluene-4-sulfonyl)-2-azaspiro[4.4]non-7-en-3-yl]methanol 
• 569656-66-2 (2S)-[(2-toluene-4-sulfonyl)-2-azaspiro[4.4]nonan-3-yl]methanol 
• 569656-64-0 3-(tert-butyl-diphenyl-silanyloxymethyl)-2-(toluene-4-sulfonyl)-2-aza-spiro[4.4]non-7-ene 
• 569656-62-8 [6-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyl)-5-aza-spiro[2.4]hept-1-yl]-methanol 
• 1025889-74-0 1-bromomethyl-6-(tert-butyl-diphenyl-silanyloxymethyl)-5-(toluene-4-sulfonyl)-5-aza-spiro[2.4]heptane 
• 569656-63-9 (2S)(2-tert-butyldiphenylsilyloxymethyl)-4,4-diallyl-1-(toluene-4-sulfonyl)pyrrolidine 
• 569656-61-7 (5S,2E,Z)[(5-tert-butyldiphenylsilyloxymethyl)-1-(toluene-4-sulfonyl)pyrrolidin-3-ylidene]ethanol 

Relevant articles and documents

Synthesis of spirocycles via ring closing metathesis of heterocycles carrying gem-diallyl substituents obtained via ring opening of (halomethyl)cyclopropanes with allyltributyltin

In the presence of allyl tri-n-butyltin-AlBN, cyclopropylmethyl bromides/xanthates undergo ring-opening reaction with concomitant formation of geminal diallyl derivatives in good yields. The ring closing metathesis reactions on geminal diallyl derivatives with Grubbs' catalyst provided spirocyclopentenyl products. Combination of these two methodologies has been applied to the synthesis of mono-, bis-cyclopentyl-carbohydrates as well as spirocyclopentylproline derivatives.