57-37-4

Basic information

• Product Name: BENACTYZINE HYDROCHLORIDE
• Synonyms: 2-(diethylamino)-ethanobenzilatehydrochloride;2-(difenyl-hydroxyacetoxy)ethyl-diethylammoniumchlorid;2-diethylaminoethylesterkyselinybenzilovehydrochlorid;aktozin;amisyl;amitakon;amizil;arkadin
• CAS NO: 57-37-4
• Molecular Formula: C20H26ClNO3
• Molecular Weight: 363.88
• EINECS: 200-324-4
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors
• Mol File: 57-37-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 177-179 °C(lit.)
• Boiling Point: 409.3°Cat760mmHg
• Flash Point: 201.4°C
• Appearance: /
• Density: 1.115g/cm³
• Vapor Pressure: 1.96E-07mmHg at 25°C
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• Merck: 14,1029
• CAS DataBase Reference: BENACTYZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENACTYZINE HYDROCHLORIDE(57-37-4)
• EPA Substance Registry System: BENACTYZINE HYDROCHLORIDE(57-37-4)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37/39-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: DD2800000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 57-37-4(Hazardous Substances Data)

Usage

Description

Benactyzine Hydrochloride, a derivative of acetylcholine, is a potent antagonist that primarily functions within the central and peripheral nervous systems. It exhibits its effects by blocking the action of acetylcholine, a neurotransmitter responsible for muscle contractions and various other physiological processes. BENACTYZINE HYDROCHLORIDE is characterized by its ability to alleviate muscle spasms and provide relief from discomfort associated with gastrointestinal disorders.

Uses

Used in Pharmaceutical Industry:
Benactyzine Hydrochloride is used as an antispasmodic agent for the treatment of gastrointestinal disorders. It works by inhibiting the action of acetylcholine, which in turn reduces muscle spasms and cramps in the gastrointestinal tract. This helps to alleviate pain and discomfort associated with conditions such as irritable bowel syndrome (IBS), peptic ulcers, and other gastrointestinal issues.
Additionally, Benactyzine Hydrochloride may also be utilized in the development of drug delivery systems to enhance its bioavailability and therapeutic outcomes. By employing various organic and metallic nanoparticles as carriers, the compound can be more effectively delivered to target tissues, improving its overall efficacy in treating gastrointestinal disorders.

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, intradermal, and intravenous routes. Human systemic effects by ingestion of very small amounts: toxic psychosis. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO, and HCl

InChI:InChI=1/C20H25NO3.ClH/c1-3-21(4-2)15-16-24-19(22)20(23,17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,23H,3-4,15-16H2,1-2H3;1H