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57-97-6

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57-97-6 Usage

Description

7,12-DIMETHYLBENZ[A]ANTHRACENE, also known as a tetraphene with methyl substituents at the 7and 12-positions, is a potent carcinogen that is present in tobacco smoke. It appears as yellow to greenish-yellow crystals or a yellow solid, odorless, with maximum fluorescence at 440 nm and exhibits a bluish-violet fluorescence in UV light.

Uses

Used in Pharmaceutical and Toxicological Research:
7,12-DIMETHYLBENZ[A]ANTHRACENE is used as a potent carcinogen for studying the effects of various treatments and substances on tumor growth and carcinogenicity. It is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading to tumor induction.
Used in Cancer Studies:
In the study of the effects of Cimicifuga racemosa (CR) extract on the growth of mammary tumors, 7,12-DIMETHYLBENZ[A]ANTHRACENE is used as an initiator to induce mammary tumors in rat liver.
Used in Skin Cancer Research:
7,12-DIMETHYLBENZ[A]ANTHRACENE is used as an initiator to cause skin cancer in CD-1 mouse models, allowing researchers to compare the anti-carcinogenic properties of various substances.
Used in Oral Cancer Research:
7,12-DIMETHYLBENZ[A]ANTHRACENE is used to induce epithelial carcinogenicity in the cheek pouch of the Syrian hamster, enabling the study of apoptotic, proliferating, and p12doc-1 profiles of normal, hyperplastic, dysplastic, and malignant oral epithelium.
Used in Mammary Tumor Studies:
7,12-DIMETHYLBENZ[A]ANTHRACENE is used to cause mammary tumors in order to examine the causes and prevention of triacylglycerol accumulation in rat liver due to tamoxifen treatment.
Used in Chemical Research:
7,12-DIMETHYLBENZ[A]ANTHRACENE, as a yellow powder, is utilized in chemical research to study its properties and potential applications in various fields.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 966, 1971 DOI: 10.1021/jo00806a023

Air & Water Reactions

Insoluble in water.

Reactivity Profile

7,12-DIMETHYLBENZ[A]ANTHRACENE is incompatible with strong oxidizing agents .

Fire Hazard

7,12-DIMETHYLBENZ[A]ANTHRACENE is combustible.

Biochem/physiol Actions

7,12-Dimethylbenz[a]anthracene has been found to be cytotoxic in nature, having carcinogenic properties. It also shows selective necrosis and hemorrhaging in the adrenal gland along with an inhibitory effect on plasma alkaline phosphatase levels. Its damaging effects are due to its ability to form charge transfer complexes by donating electrons to appropriate electron acceptors.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. A transplacental carcinogen. Poison by ingestion, intravenous, subcutaneous, intraperitoneal, and intratracheal routes. Other experimental reproductive effects. Human mutation data reported. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Purify DMBA by chromatography on alumina/toluene or *benzene. Crystallise it from acetone/EtOH. [Beilstein 5 IV 2587.]

Check Digit Verification of cas no

The CAS Registry Mumber 57-97-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57-97:
(4*5)+(3*7)+(2*9)+(1*7)=66
66 % 10 = 6
So 57-97-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H16/c1-13-7-8-15-9-10-18-11-16-5-3-4-6-17(16)12-19(18)20(15)14(13)2/h3-12H,1-2H3

57-97-6 Well-known Company Product Price

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  • (40567)  7,12-Dimethylbenz[a]anthracenesolution  certified reference material, 1000 μg/mL in methanol

  • 57-97-6

  • 000000000000040567

  • 359.19CNY

  • Detail
  • Supelco

  • (442425)  7,12-Dimethylbenz[a]anthracene  analytical standard

  • 57-97-6

  • 000000000000442425

  • 756.99CNY

  • Detail

57-97-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 7,12-dimethyltetraphene

1.2 Other means of identification

Product number -
Other names 7,12-dimethylbenzo[a]anthracene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57-97-6 SDS

57-97-6Synthetic route

7,12-dihydro-7,12-dimethylbenzanthracene-7,12-diol
2518-00-5

7,12-dihydro-7,12-dimethylbenzanthracene-7,12-diol

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With hydrogenchloride; acetic acid; tin(ll) chloride
With 2TiCl2*LiAlH4 In tetrahydrofuran for 3h; Heating; Yield given;
Multi-step reaction with 2 steps
1: 57 percent aq. HI
2: 1 percent bisulfite solution / Heating
View Scheme
Multi-step reaction with 2 steps
1: methanol; sulfuric acid
2: potassium; benzene
View Scheme
benz[a]anthracene-7,12-dione
2498-66-0

benz[a]anthracene-7,12-dione

methylmagnesium bromide
75-16-1

methylmagnesium bromide

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
Reaktion ueber mehrere Stufen;
7,12-dimethyl-7,12-dihydro-benz[a]anthracene
35281-31-3

7,12-dimethyl-7,12-dihydro-benz[a]anthracene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With sulfur at 200℃;
With sulfur at 210 - 220℃;
7-iodomethyl-12-methylbenz[a]anthracene
27018-50-4

7-iodomethyl-12-methylbenz[a]anthracene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With 1,4-dioxane; hydrogenchloride; tin(ll) chloride
With bisulfite solution Heating; Yield given;
7-(12-Methylbenzanthryl)acetic acid
63020-22-4

7-(12-Methylbenzanthryl)acetic acid

(E)-3-Ureido-but-2-enoic acid ethyl ester
5435-44-9, 22243-66-9

(E)-3-Ureido-but-2-enoic acid ethyl ester

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
at 180 - 185℃;
7-(12-Methylbenzanthryl)acetic acid
63020-22-4

7-(12-Methylbenzanthryl)acetic acid

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With tin(IV) chloride at 110 - 120℃;
With zinc(II) chloride at 180 - 185℃;
7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene
63018-76-8

7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With sodium; benzene
With potassium; benzene
7-bromo-12-methyl-benz[a]anthracene
81830-40-2

7-bromo-12-methyl-benz[a]anthracene

methyl iodide
74-88-4

methyl iodide

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With n-butyllithium; diethyl ether; benzene
diethyl ether
60-29-7

diethyl ether

acetic acid-(12-methyl-benz[a]anthracen-7-yl ester)
17526-35-1

acetic acid-(12-methyl-benz[a]anthracen-7-yl ester)

methylmagnesium bromide
75-16-1

methylmagnesium bromide

benzene
71-43-2

benzene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
Reaktion ueber mehrere Stufen;
7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene
2518-01-6

7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene

A

8,13-epoxy-8,13-dihydro-8,13-dimethyl-1a,7a-naphtho-8a,12a-benzoxepin
65273-21-4

8,13-epoxy-8,13-dihydro-8,13-dimethyl-1a,7a-naphtho-8a,12a-benzoxepin

B

7,12-dihydro-7,12-dimethylbenzanthracene-7,12-diol
2518-00-5

7,12-dihydro-7,12-dimethylbenzanthracene-7,12-diol

C

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
In chlorobenzene for 10h; Product distribution; Heating; other time, other solvent;
hydrogenchloride
7647-01-0

hydrogenchloride

methanol
67-56-1

methanol

7,12-dimethyl-7,12-dihydro-benz[a]anthracen-7-ol
77318-30-0

7,12-dimethyl-7,12-dihydro-benz[a]anthracen-7-ol

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With hydrogen iodide; acetic acid
acetic acid-(12-methyl-benz[a]anthracen-7-yl ester)
17526-35-1

acetic acid-(12-methyl-benz[a]anthracen-7-yl ester)

excessive methyl magnesium bromide

excessive methyl magnesium bromide

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With diethyl ether; benzene Reaktion ueber mehrere Stufen;
12-methyltetraphen-7(12H)-one
73038-40-1

12-methyltetraphen-7(12H)-one

methyl magnesium halide

methyl magnesium halide

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With diethyl ether; benzene anschliessend mit wss. NH4Cl behandeln;
7-(12-Methylbenzanthryl)acetic acid
63020-22-4

7-(12-Methylbenzanthryl)acetic acid

tin(IV) chloride
7646-78-8

tin(IV) chloride

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
at 110 - 120℃;
diethyl ether
60-29-7

diethyl ether

7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene
63018-76-8

7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene

benzene
71-43-2

benzene

potassium

potassium

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

diethyl ether
60-29-7

diethyl ether

7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene
63018-76-8

7,12-dimethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene

benzene
71-43-2

benzene

sodium

sodium

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

diethyl ether
60-29-7

diethyl ether

7,12-diethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene

7,12-diethoxy-7,12-dimethyl-7,12-dihydro-benz[a]anthracene

benzene
71-43-2

benzene

sodium

sodium

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

benz[a]anthracene-7,12-dione
2498-66-0

benz[a]anthracene-7,12-dione

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: benzene; diethyl ether / Ambient temperature
2: 2TiCl2*LiAlH4 / tetrahydrofuran / 3 h / Heating
View Scheme
Multi-step reaction with 3 steps
1: benzene; diethyl ether / 24 h / Ambient temperature
2: 57 percent aq. HI
3: 1 percent bisulfite solution / Heating
View Scheme
Multi-step reaction with 2 steps
1: diethyl ether; benzene / Behandlung des nach der Hydrolyse erhaltenen Reaktionsprodukts mit wss. HI in Methanol
2: SnCl2; concentrated aqueous HCl; dioxane
View Scheme
12-methylbenzo[a]anthracene
2422-79-9

12-methylbenzo[a]anthracene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous HI
2: SnCl2; concentrated aqueous HCl; dioxane
View Scheme
Multi-step reaction with 2 steps
1: aqueous HI
2: SnCl2; concentrated aqueous HCl; dioxane
View Scheme
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-bis(bromomethyl)benz[a]anthracene
34331-98-1

7,12-bis(bromomethyl)benz[a]anthracene

Conditions
ConditionsYield
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane for 3h; Inert atmosphere; Reflux;65.2%
With carbon disulfide; bromine unter Kuehlung;
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

2'-Deoxyguanosine
961-07-9

2'-Deoxyguanosine

A

2-Amino-7-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one
138606-34-5

2-Amino-7-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one

B

2-Amino-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one
138877-58-4

2-Amino-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one

C

2-Amino-7-(12-methyl-benzo[a]anthracen-7-ylmethyl)-1,7-dihydro-purin-6-one
138877-59-5

2-Amino-7-(12-methyl-benzo[a]anthracen-7-ylmethyl)-1,7-dihydro-purin-6-one

D

2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,9-dihydro-purin-6-one
138898-82-5

2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,9-dihydro-purin-6-one

Conditions
ConditionsYield
With potassium perchlorate In N,N-dimethyl-formamide electrolysis; Further byproducts given;A 55%
B 10%
C 12%
D 13%
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

2'-deoxy-D-adenosine
958-09-8

2'-deoxy-D-adenosine

A

7-(7-Methyl-benzo[a]anthracen-12-ylmethyl)-7H-purin-6-ylamine
138606-33-4

7-(7-Methyl-benzo[a]anthracen-12-ylmethyl)-7H-purin-6-ylamine

B

3-(12-Methyl-benzo[a]anthracen-7-ylmethyl)-3H-purin-6-ylamine
138877-60-8

3-(12-Methyl-benzo[a]anthracen-7-ylmethyl)-3H-purin-6-ylamine

Conditions
ConditionsYield
With potassium perchlorate In N,N-dimethyl-formamide electrolysis;A 45%
B 55%
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

trans-7,12-dihydro-7,12-dimethylbenzanthracene
23660-33-5

trans-7,12-dihydro-7,12-dimethylbenzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen iodide In acetic acid for 0.25h; Heating; Title compound not separated from byproducts;A 50%
B 25%
para-xylene
106-42-3

para-xylene

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

silver perchlorate

silver perchlorate

[Ag2(7,12-dimethylbenz[a]anthracene)2(perchlorato)2](p-xylene)

[Ag2(7,12-dimethylbenz[a]anthracene)2(perchlorato)2](p-xylene)

Conditions
ConditionsYield
In xylene under Ar; 7,12-dimethylbenz(a)anthracene added to p-xylene soln. of AgClO4 (molar ratio 1:1); stirred for 10 min; filtered; filtrate layered with n-hexane; sealed under Ar and wrapped with Al foil; stored at room temp. for 2 weeks; elem. anal.;49%
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

chromium(0) hexacarbonyl
199620-14-9, 13007-92-6

chromium(0) hexacarbonyl

(η6-7,12-dimethylbenz{a}anthracene)tricarbonylchromium
146596-56-7

(η6-7,12-dimethylbenz{a}anthracene)tricarbonylchromium

Conditions
ConditionsYield
In tetrahydrofuran; dibutyl ether refluxing under nitrogen for 7 h;; filtration; recrystn. from toluene-hexane at -78°C; purifn. by sublimation; elem. anal.;32%
maleic anhydride
108-31-6

maleic anhydride

7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-dimethyl-7,12-dihydro-7,12-ethano-benz[a]anthracene-13,14-dicarboxylic acid-anhydride
6632-71-9

7,12-dimethyl-7,12-dihydro-7,12-ethano-benz[a]anthracene-13,14-dicarboxylic acid-anhydride

Conditions
ConditionsYield
With benzene
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-bis-acetoxymethyl-benz[a]anthracene
63018-62-2

7,12-bis-acetoxymethyl-benz[a]anthracene

Conditions
ConditionsYield
With lead(IV) acetate; acetic acid
Multi-step reaction with 2 steps
1: carbon disulfide; bromine / unter Kuehlung
2: potassium acetate
View Scheme
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene
2518-01-6

7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With carbon disulfide mit Sauerstoff unter Belichtung;
With oxygen for 4h; Irradiation;
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

Conditions
ConditionsYield
With pyridine; osmium(VIII) oxide; benzene Behandeln des Reaktionsprodukts in Dichlormethan mit wss. KOH und Mannit;
(i) OsO4, Py, benzene, (ii) mannitol, aq. NaOH, CH2Cl2; Multistep reaction;
With pyridine; osmium(VIII) oxide
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

A

7,12-dimethyl-5,6-dihydrobenzanthracene
35281-29-9

7,12-dimethyl-5,6-dihydrobenzanthracene

B

8,9,10,11-tetrahydro-7,12-dimethylbenzanthracene
25486-91-3

8,9,10,11-tetrahydro-7,12-dimethylbenzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

D

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene
73712-72-8

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In ethyl acetate under 2585.7 Torr; for 22h; Ambient temperature; Title compound not separated from byproducts;A 12 % Chromat.
B 64 % Chromat.
C 18 % Chromat.
D 6 % Chromat.
With hydrogen; platinum(IV) oxide In ethyl acetate under 2585.7 Torr; for 22h; Ambient temperature;A 12 % Chromat.
B 64 % Chromat.
C 18 % Chromat.
D 6 % Chromat.
With hydrogen; platinum(IV) oxide; iron(II) chloride In hydrogenchloride under 1034.3 Torr; for 24h; Ambient temperature; Further byproducts given. Title compound not separated from byproducts;A 11 % Chromat.
B 6 % Chromat.
C 15 % Chromat.
D 62 % Chromat.
With hydrogen; platinum(IV) oxide; iron(II) chloride In hydrogenchloride under 1034.3 Torr; for 24h; Ambient temperature; Further byproducts given;A 11 % Chromat.
B 6 % Chromat.
C 15 % Chromat.
D 62 % Chromat.
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

A

7,12-dimethyl-5,6-dihydrobenzanthracene
35281-29-9

7,12-dimethyl-5,6-dihydrobenzanthracene

trans-7,12-dihydro-7,12-dimethylbenzanthracene
23660-33-5

trans-7,12-dihydro-7,12-dimethylbenzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

D

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene
73712-72-8

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide; iron(II) chloride In hydrogenchloride under 1034.3 Torr; for 24h; Ambient temperature; Further byproducts given;A 11 % Chromat.
B 6 % Chromat.
C 15 % Chromat.
D 62 % Chromat.
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

A

7,12-dimethyl-5,6-dihydrobenzanthracene
35281-29-9

7,12-dimethyl-5,6-dihydrobenzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate under 1034.3 Torr; for 8h; Ambient temperature;A 80 % Spectr.
B 20 % Spectr.
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

A

8,9,10,11-tetrahydro-7,12-dimethylbenzanthracene
25486-91-3

8,9,10,11-tetrahydro-7,12-dimethylbenzanthracene

trans-7,12-dihydro-7,12-dimethylbenzanthracene
23660-33-5

trans-7,12-dihydro-7,12-dimethylbenzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

D

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene
73712-72-8

5,6,8,9,10,11-hexahydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In acetic acid; ethyl acetate under 1551.4 Torr; for 22h; Further byproducts given;A 10 % Chromat.
B 10 % Chromat.
C 19 % Chromat.
D 55 % Chromat.
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

A

[3H]-7-Hydroxymethyl-12-methylbenz[a]anthracene
568-75-2

[3H]-7-Hydroxymethyl-12-methylbenz[a]anthracene

B

7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene
2518-01-6

7,12-epidioxy-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With oxygen In octane Product distribution; Irradiation; Oxidative degradation,initiated Co60 source(1-5 W/kg) ;other solvents;relative values k/ko (ko = benzo<a>pyrene)</a>;
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

cis-7,12-dihydro-7,12-dimethylbenzanthracene
24316-23-2

cis-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With hydrogen iodide In acetic acid for 1h; Heating;85 % Turnov.
Multi-step reaction with 2 steps
1: 50 percent / HI / acetic acid / 0.25 h / Heating
2: HI / acetic acid / 1 h / Heating
View Scheme
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

2'-Deoxyguanosine
961-07-9

2'-Deoxyguanosine

A

7,12-dihydroxymethylbenz[a]anthracene
2564-65-0

7,12-dihydroxymethylbenz[a]anthracene

B

2-Amino-7-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one
138606-34-5

2-Amino-7-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one

C

2-Amino-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one
138877-58-4

2-Amino-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,7-dihydro-purin-6-one

D

2-Amino-7-(12-methyl-benzo[a]anthracen-7-ylmethyl)-1,7-dihydro-purin-6-one
138877-59-5

2-Amino-7-(12-methyl-benzo[a]anthracen-7-ylmethyl)-1,7-dihydro-purin-6-one

E

2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,9-dihydro-purin-6-one
138898-82-5

2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-(7-methyl-benzo[a]anthracen-12-ylmethyl)-1,9-dihydro-purin-6-one

Conditions
ConditionsYield
With potassium perchlorate In N,N-dimethyl-formamide Mechanism; other nucleosides; electrolysis;
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

trans-7,12-dihydro-7,12-dimethylbenzanthracene
23660-33-5

trans-7,12-dihydro-7,12-dimethylbenzanthracene

Conditions
ConditionsYield
With ammonia; lithium
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

[3H]-12-Hydroxymethyl-7-methylbenz[a]anthracene
568-70-7

[3H]-12-Hydroxymethyl-7-methylbenz[a]anthracene

Conditions
ConditionsYield
(i) NBS, (ii) aq. NaOH; Multistep reaction;
7,12-dimethyl-1,2-benzanthracene
57-97-6

7,12-dimethyl-1,2-benzanthracene

7,12-dimethyl-5,6-dihydrobenzanthracene
35281-29-9

7,12-dimethyl-5,6-dihydrobenzanthracene

Conditions
ConditionsYield
With hydrogen; Pd/SrCO3

57-97-6Relevant articles and documents

Synthesis of 7,12-Dimethylbenzanthracene and Its 1,2,3,4-Tetrahydro Derivative

Harvey, Ronald G.,Cortez, Cecilia

, p. 5023 - 5024 (1986)

-

Reductive Methylation of Polycyclic Aromatic Quinones

Konieczny, Maria,Harvey, Ronald G.

, p. 1308 - 1310 (2007/10/02)

-

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