57027-76-6

Basic information

• Product Name: 2-(3-bromopropyl)phenol
• Synonyms: 2-(3-bromopropyl)phenol
• CAS NO: 57027-76-6
• Molecular Weight: 215.09
• Mol File: 57027-76-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-bromopropyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-bromopropyl)phenol(57027-76-6)
• EPA Substance Registry System: 2-(3-bromopropyl)phenol(57027-76-6)

Safety Data

• Hazardous Substances Data: 57027-76-6(Hazardous Substances Data)

Usage

Classification

Organic compound

Derivative

Brominated derivative of phenol

Usage

Disinfectant and preservative in cosmetics, soaps, and pharmaceuticals

Antimicrobial properties

Effective against a wide range of bacteria and fungi

Chemical structure

Phenol ring with a bromine atom and a propyl group attached

Benefits

Prevents the growth of microorganisms and extends the shelf life of products

Precautions

Potential toxicity and irritant properties; handle with care

Upstream product

• 1481-92-1 2-(3-hydroxypropyl)phenol 
• 501-97-3 4-hydroxyphenylpropionic acid 
• 10493-37-5 3-(2-methoxyphenyl)propan-1-ol 
• 6342-77-4 2-methoxy-benzenepropanoic acid 
• 146253-19-2 3-(2-methoxyphenyl)propyl methanesulfonate 

Downstream Products

• 1261033-20-8 C₁₀H₁₅NO₃S 
• 1221741-01-0 (E)-N-(3-(2-hydroxyphenyl)propyl)buta-1,3-diene-1-sulfonamide 
• 51796-03-3 6-(o-hydroxyphenyl)-1-hexene 
• 1261034-04-1 C₁₅H₁₆N₂O₅S 
• 1261034-02-9 C₂₁H₃₀N₂O₅SSi 
• 1261034-01-8 C₁₆H₂₉NO₃SSi 
• 1221740-99-3 (E)-N-(3-(2-(tert-butyldimethylsilyloxy)phenyl)propyl)buta-1,3-diene-1-sulfonamide 
• 1221740-97-1 3-(2-(tert-butyldimethylsilyloxy)phenyl)propan-1-amine 
• 1221741-12-3 (2-(3-azidopropyl)phenoxy)(tert-butyl)dimethylsilane 
• 1221741-11-2 2-(3-azidopropyl)phenol 

Relevant articles and documents

Synthesis and PGE2 inhibitory activity of novel diarylheptanoids

Prostaglandin E2 (PGE2) is a lipid mediator of inflammation and its inhibition has become a popular drug target due to its harmful physiological roles. Diarylheptanoids are one class of compounds that have shown successful inhibition of PGE2. This paper reports the synthesis and PGE2 inhibitory activity of a series of analogues of a naturally occurring diarylheptanoid. The most efficacious compounds were examined for dose-dependent PGE2 inhibition. Among several promising compounds, the lead candidate exhibited an IC50 value of 0.56 ng/μL or 1.7 μM with no detectable toxicity at the highest dose of 10 ng/μL.

Tandem phenolic oxidative amidation-intramolecular diels-alder reaction: An approach to the himandrine core

An oxidative cyclization of dienic sulfonamides mediated by iodobenzene diacetate in TFA, followed by a tandem intramolecular Diels-Alder reaction, achieves desymmetrization of a "locally symmetrical" dienone with good levels of diastereoselectivity and leads to valuable synthetic intermediates for the himandrine alkaloids.