570424-05-4

Basic information

• Product Name: 5-(Pyrrolidin-3-yl)-2H-tetrazole
• Synonyms: 5-(Pyrrolidin-3-yl)-2H-tetrazole;5-(3-Pyrrolidinyl)-1H-tetrazole;2H-Tetrazole,5-(3-pyrrolidinyl)-
• CAS NO: 570424-05-4
• Molecular Formula: C₅H₉N₅
• Molecular Weight: 139.15846
• Mol File: 570424-05-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 335℃
• Flash Point: 157℃
• Appearance: /
• Density: 1.301
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-(Pyrrolidin-3-yl)-2H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(Pyrrolidin-3-yl)-2H-tetrazole(570424-05-4)
• EPA Substance Registry System: 5-(Pyrrolidin-3-yl)-2H-tetrazole(570424-05-4)

Safety Data

• Hazardous Substances Data: 570424-05-4(Hazardous Substances Data)

Usage

General Description

5-(Pyrrolidin-3-yl)-2H-tetrazole is a chemical compound with the molecular formula C7H10N6. It is a tetrazole derivative, which is a class of compounds known for their diverse pharmacological activities. 5-(Pyrrolidin-3-yl)-2H-tetrazole has been studied for its potential applications in drug discovery and development, particularly in the field of medicinal chemistry. It exhibits promising biological properties and has shown potential as a versatile building block for the synthesis of novel pharmaceutical compounds. Additionally, this compound has also been investigated for its potential use in materials science and as a precursor for the synthesis of functionalized tetrazole derivatives with a variety of applications. Overall, 5-(Pyrrolidin-3-yl)-2H-tetrazole is a versatile and potentially valuable compound with a wide range of potential applications.

InChI:InChI=1/C5H9N5/c1-2-6-3-4(1)5-7-9-10-8-5/h4,6H,1-3H2,(H,7,8,9,10)

Relevant articles and documents

BENZIMIDAZOLE AND AZA-BENZIMIDAZOLE CARBOXAMIDES

This invention provides compounds of Formula I which are PAFR antagonists: I and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and can be used in methods for treating atherosclerosis and preve

NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS

A subject of the invention is the compounds of formula (I): in which either R1 represents H, OH, NH2, —(CH2)m—NRaRb(m=0.1 or 2),Ra and Rb represent H, linear, branched or cyclic (C1 -C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)— alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rd or C(O)Rd;or Ra and Rb with N form an Rc radical;Rc represents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted;Rd represents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens;or R1 represents Rc or CHReRc or CHReRd;Re represents H, OH, NH2, NH—(C1-C6)-alk or N-(C1-C6)-alk2, or NH—(C1-C7)-acyl or NHRc;R2 represents H, (CH2)m—NRaRb, Rc, CHReRc or CHReRd, and R′2 represents H; it being understood that R1 and R2 cannot at the same time be H or that R1 and R2 or R2 and R1 cannot be one (CH2)m—NRaRb or Rc or H and the other one OH, or one H and the other one NH2, or one H and the other one (CH2)m—NRaRb in which Ra and Rb represent H or alkyl or C(O)Rd, in which Rd represents an unsubstituted alkyl or cycloalkyl; or R1 has the above definition except H and R2 and R′2 together represent gem dialkyl or alkyl-oxime, or R2 and R′2 represent respectively Rc or Rd and OH, NH2, NHRc or NHRf, Rf being a (C1-C7) acyl radical;or R1 represents H and R2 and R′2 together represent alkyl-oxime or one represents Rc and the other one represents OH, NH2, NHRc or NHRf;n is 0 or 1;R3 and R′3 represent H or (C1-C6) alkyl optionally substituted by 1 to 3 halogens or R3 represents (C1-C6) alkoxy carbonyl and R′3 represents H;R4 represents methyl optionally substituted by halogen;R5 represents H, (C1-C6) alkyl or (C7-C12) arylalkyl;R6 represents H, fluorine, NO2, CF3 or CN;in the form of enantiomers or mixtures, as well as their salts with acids and bases; their preparation and their application as anti-bacterials, in both human and veterinary medicine.