571-25-5 Usage
Description
5-Androsten-17beta-ol-3-one, also known as (17β)-17-hydroxyandrost-5-en-3-one, is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is a steroidal molecule with a unique structure that makes it valuable in the development of new drugs and therapies.
Uses
Used in Pharmaceutical Industry:
5-Androsten-17beta-ol-3-one is used as a reagent for the synthesis of new hedgehog signaling inhibitors, which are being explored for their potential applications in cancer treatments. Hedgehog signaling plays a crucial role in the development and progression of various types of cancer, and inhibiting this pathway can help in the development of novel therapeutic strategies.
In the field of cancer research and treatment, 5-Androsten-17beta-ol-3-one is used as a starting material for the development of compounds that target the hedgehog signaling pathway. This pathway is often dysregulated in cancer cells, leading to uncontrolled cell growth and tumor formation. By inhibiting this pathway, the compounds synthesized using 5-Androsten-17beta-ol-3-one may help in the treatment of various types of cancer, including solid tumors and leukemia.
Additionally, 5-Androsten-17beta-ol-3-one may also be used in the development of other pharmaceutical applications, such as hormone replacement therapies, contraceptives, and treatments for various endocrine disorders. Its unique structure and properties make it a versatile compound for the synthesis of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 571-25-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 571-25:
(5*5)+(4*7)+(3*1)+(2*2)+(1*5)=65
65 % 10 = 5
So 571-25-5 is a valid CAS Registry Number.
571-25-5Relevant articles and documents
o-Nitrophenylethylene glycol as photoremovable protective group for aldehydes and ketones: syntheses, scope, and limitations
Gravel, D.,Herbert, J.,Thoraval, D.
, p. 400 - 410 (2007/10/02)
The preparation of o-nitophenylethylene glycol is described along with its application as a photolabile protective group for aldehydes and ketones.Formation of the acetals and ketals is achieved in good to high yields in the usual manner and deprotection is carried out in fair to high yield, by photolysis at 350 nm in an inert solvent such as benzene.Because of the particular nature of the present protective group, its stability to basic and acidic conditions has been examined and is reported to complete the scope and limitations aspect.From a mechanistic point of view, the isolation and characterisation of o-nitroso-α-hydroxyacetophenone as the spent reagent demonstrates a mechanistic link with the known o-nitrobenzaeldehyde to o-nitrobenzoic acid photorearrangement.
