57102-09-7 Usage
Description
1,25-dihydroxy-previtamin D(3), also known as 1α,25-Dihydroxyprevitamin D3, is a biologically active form of Vitamin D3. It plays a crucial role in various cellular processes and is closely related to Vitamin D (V676045). 1,25-dihydroxy-previtamin D(3) is known for its ability to stimulate the expression and translocation of protein kinase Calpha and Cdelta, which are essential for maintaining cellular homeostasis.
Uses
Used in Pharmaceutical Industry:
1,25-dihydroxy-previtamin D(3) is used as a therapeutic agent for various health conditions due to its role in cellular processes. It is particularly effective in managing and treating conditions related to Vitamin D deficiency, as well as certain bone disorders and immune system-related issues.
Used in Research Applications:
In the field of scientific research, 1,25-dihydroxy-previtamin D(3) is used as a research tool to study the effects of Vitamin D on cellular processes. Its ability to stimulate protein kinase Calpha and Cdelta makes it a valuable compound for understanding the underlying mechanisms of various diseases and potential therapeutic interventions.
Used in Nutritional Supplements:
1,25-dihydroxy-previtamin D(3) is also used as an ingredient in nutritional supplements to support overall health and well-being. It helps maintain optimal levels of Vitamin D in the body, which is essential for maintaining strong bones, a healthy immune system, and proper cellular function.
Check Digit Verification of cas no
The CAS Registry Mumber 57102-09-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,1,0 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 57102-09:
(7*5)+(6*7)+(5*1)+(4*0)+(3*2)+(2*0)+(1*9)=97
97 % 10 = 7
So 57102-09-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h9-11,18,22-25,28-30H,6-8,12-17H2,1-5H3/b11-10-/t18-,22+,23-,24+,25-,27-/m1/s1
57102-09-7Relevant articles and documents
Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1α,25-dihydroxyvitamin D analogs
Chen, Yong-Jun,Gao, Ling-Jie,Murad, Ibrahim,Verstuyf, Annemieke,Verlinden, Lieve,Verboven, Christel,Bouillon, Roger,Viterbo, Davide,Milanesio, Marco,Van Haver, Dirk,Vandewalle, Maurits,De Clercq, Pierre J.
, p. 257 - 267 (2007/10/03)
A novel series of analogs of 1.25-dihydroxyvitamin D3, the hormonally active metabolite of vitamin D3, characterised by the presence of a trans-fused decalin CD-ring system, possesses surprising biological activities in combination w
14-Epi stereoisomers of 25-hydroxy- and 1α,25-dihydroxyvitamin D3: Synthesis, isomerization to previtamins, and biological studies
Maynard,Trankle,Norman,Okamura
, p. 2387 - 2393 (2007/10/02)
The C-14 epimers of vitamin D, 14-epi-25-hydroxyvitamin D3 (4) and 14- epi-1α,25-dihydroxyvitamin D3 (5), were synthesized, and their isomerization via [1,7]-sigmatropic hydrogen shifts to the corresponding previtamin forms (4' and 5
1α,25-dihydroxyprevitamin D3: Synthesis of the 9,14,19,19,19,-pentadeuterio derivative and a kinetic study of its [1,7]-sigmatropic shift to 1α,25-dihytdroxyvitamin D31
Curtin,Okamura
, p. 6958 - 6966 (2007/10/02)
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