57122-94-8

Basic information

• Product Name: p-Azidophenacyl Bromide-1-14C
• Synonyms: 1-(4-Azidophenyl)-2-bromo-ethanone-1-14C
• CAS NO: 57122-94-8
• Molecular Formula: C714CH6BrN3O
• Molecular Weight: 0
• Product Categories: Isotope Labeled Compounds;Photoaffinity Labels;Isotope Labelled Compounds;MTS & Sulfhydryl Active Reagents
• Mol File: 57122-94-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 68-70°C
• Appearance: /
• CAS DataBase Reference: p-Azidophenacyl Bromide-1-14C(CAS DataBase Reference)
• NIST Chemistry Reference: p-Azidophenacyl Bromide-1-14C(57122-94-8)
• EPA Substance Registry System: p-Azidophenacyl Bromide-1-14C(57122-94-8)

Safety Data

• Hazardous Substances Data: 57122-94-8(Hazardous Substances Data)

Usage

Description

p-Azidophenacyl Bromide-1-14C is a radiolabeled, off-white crystalline solid that serves as a versatile photolabile bifunctional reagent. It is particularly useful for investigating the active sites of sulfhydryl enzymes, especially those with a highly reactive cysteine residue at the active site. Additionally, it is employed to study the nature of the ribosomal binding site of E. coli tRNAVal.

Uses

Used in Enzyme Research:
p-Azidophenacyl Bromide-1-14C is used as a research tool for studying the active sites of sulfhydryl enzymes. Its application is based on its ability to interact with the reactive cysteine residues at the active sites, providing valuable insights into enzyme function and structure.
Used in E. coli tRNAVal Ribosomal Binding Site Studies:
p-Azidophenacyl Bromide-1-14C is used as a research reagent to investigate the nature of the ribosomal binding site of E. coli tRNAVal. This application is due to its capacity to interact with and provide information on the binding site's characteristics, which is crucial for understanding the translation process in bacteria.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, p-Azidophenacyl Bromide-1-14C is used as a research compound for the development of new drugs targeting sulfhydryl enzymes. Its application is based on its ability to help researchers understand the enzyme's active site, which can aid in the design of more effective and targeted therapeutic agents.
Used in Biochemical Education:
p-Azidophenacyl Bromide-1-14C is used as an educational tool in biochemistry, particularly in laboratory settings where students can learn about enzyme active sites and ribosomal binding through hands-on experience with this reagent. Its application in this context is to enhance understanding of complex biochemical processes and techniques.