57151-38-9

Basic information

• Product Name: 1-amino-2-(p-methoxyphenyl)-1-phenylethane
• Synonyms: 1-amino-2-(p-methoxyphenyl)-1-phenylethane
• CAS NO: 57151-38-9
• Molecular Weight: 227.306
• Mol File: 57151-38-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-amino-2-(p-methoxyphenyl)-1-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-2-(p-methoxyphenyl)-1-phenylethane(57151-38-9)
• EPA Substance Registry System: 1-amino-2-(p-methoxyphenyl)-1-phenylethane(57151-38-9)

Safety Data

• Hazardous Substances Data: 57151-38-9(Hazardous Substances Data)

Upstream product

• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 71-43-2 benzene 
• 4314-68-5 3-(4-methoxyphenyl)-2-phenylpropionic acid 
• 24845-40-7 2-(4-methoxyphenyl)acetophenone 
• 67-56-1 methanol 
• 50882-23-0 α'-nitro-4-methoxy-trans-stilbene 
• 1694-19-5 p-methoxystilbene 
• 123-11-5 4-methoxy-benzaldehyde 
• 622-42-4 1-nitro-1-phenylmethane 

Downstream Products

• 57151-28-7 1-(2-methoxy-phenyl)-4-[2-(4-methoxy-phenyl)-1-phenyl-ethyl]-piperazine 
• 135192-20-0 cis-Pt(NH3)Cl2(2-(4-methoxyphenyl)-1-phenylethylamine) 
• 135192-20-0 trans-Pt(NH3)Cl2(2-(4-methoxyphenyl)-1-phenylethylamine) 
• 57151-23-2 1-cycloheptyl-4-[2-(4-methoxy-phenyl)-1-phenyl-ethyl]-piperazine 
• 618-36-0 rac-methylbenzylamine 
• 131475-31-5 N-(2,2-diethoxyethyl)amino-2-p-methoxyphenyl-1-phenylethane 
• 34492-35-8 C₃₄H₄₀Cl₂N₃O₂PS 

Relevant articles and documents

10,5-(Iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene and derivatives. Potent PCP receptor ligands

IDDC (3, 10,5-(iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene) and a series of substituted derivatives were synthesized and evaluated in vitro for their ability to displace tritiated MK-801 ([3H]-2) from its specific binding site in guinea pig brain homogenate. Substitution at the 3- position of 3 with bromine, chlorine, and fluorine led to increased binding affinity. In contrast, substitution of donor groups at the 3-position gave decreased binding affinities, as did all substitutions at the 7-position and on nitrogen. Where racemic mixtures were resolved, the (+)-optical antipodes were more active than their enantiomers or racemates. The most active ligand found in this study was (+)-13e (IC50 = 15.5 ± 4.5 nM). The affinity of (+)-13e for the PCP receptor makes it among the most potent ligands known. In vitro neuroprotection was demonstrated by 3, (+)-3, and (+)-6 (N-Me-IDDC) against glutamate-induced cell death in rat hippocampal cells.