5717-16-8Relevant articles and documents
Pd(ii)/Zn co-catalyzed chemo-selective hydrogenation of α-methylene-γ-keto carboxylic acids
Zhang, Xuexin,Gao, Yang,Laishram, Ronibala Devi,Li, Kangkui,Yang, Yong,Zhan, Yong,Luo, Yang,Fan, Baomin
, p. 2174 - 2181 (2019/02/27)
An efficient Pd/Zn co-catalyzed chemo-selective hydrogenation of α-methylene-γ-keto carboxylic acids is described. This methodology offers a divergent synthesis of α-methyl-γ-keto carboxylic acids, α-methylcarboxylic acids, and lactones starting from α-me
A simple synthesis of α-methyl-γ-keto acids
Pawar,Waghmare,Lokhande
, p. 2549 - 2551 (2007/10/03)
The reaction of the anion derived from α-marpholinonitriles with methyl acrylate in excess of NaH in DMF gives γ-keto acids in high yield. This process is highly convenient for the synthesis of various α-substituted-γ-keto acids, which can be easily converted to naturally occurring α-substituted -γ-lactones.
Development of Chiral Nucleophilic Pyridine Catalysts: Applications in Asymmetric Quaternary Carbon Synthesis
Shaw, Scott A.,Aleman, Pedro,Vedejs, Edwin
, p. 13368 - 13369 (2007/10/03)
TADMAP (1a), a new chiral DMAP catalyst, has been designed to place a C(3)-benzylic trityl group over one face of the pyridine ring, while a C(3)-benzylic acetoxy group creates a chirotopic environment on the other face. TADMAP was prepared in four steps