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Method for preparing atomoxetine hydrochloride
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Paragraph 0009, (2017/05/20)
The invention belongs to the technical field of medicines, and particularly relates to a method for preparing atomoxetine hydrochloride which is a medicine for treating attention deficit hyperactivity disorder. The atomoxetine hydrochloride is made of commercially easily available intermediates 3-methylamino-1-propiophenone hydrochloride. The method includes carrying out reduction, salt decomposition, resolving, substitution and salt forming to obtain the atomoxetine hydrochloride. The method has the advantages that technologies for preparing the atomoxetine hydrochloride are simple and stable and are easy and convenient to implement, high in yield and applicable to industrial production, and sufficient raw materials can be provided for research and development of medicines.